For-Met-Leu-Phe-OH

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Names

[ CAS No. ]:
59880-97-6

[ Name ]:
For-Met-Leu-Phe-OH

[Synonym ]:
N-Formyl-Met-Leu-Phe
formyl-Met-Leu-Phe
N-formyl-methionyl-leucyl-phenylalanine
L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)-
Chemotactic peptide
formyl-MLF
MFCD00012901
N-Formyl-L-methionyl-L-leucyl-L-phenylalanine
N-Formylmethionine leucyl-phenylalanine
EINECS 200-462-5
L-Phenylalanine, N-formyl-L-methionyl-L-leucyl-
N-formyl-L-methyonyl-L-leucyl-L-phenylalanine
NformylLmethionylLleucylLphenylalaninol

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
783.5±60.0 °C at 760 mmHg

[ Melting Point ]:
271-274 °C(lit.)

[ Molecular Formula ]:
C21H31N3O5S

[ Molecular Weight ]:
437.553

[ Flash Point ]:
427.6±32.9 °C

[ Exact Mass ]:
437.198456

[ PSA ]:
149.90000

[ LogP ]:
3.13

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.551

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMF: 50 mg/mL, clear, colorless

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
SJ6050000

[ HS Code ]:
2922299090

Synthetic Route

Precursor & DownStream

Precursor

  • N-FORMYL-MET-LEU-PHE BENZYL ESTER
  • Boc-Leu-OSu
  • H-Phe-ObzlTos
  • Leu-Phe-OBzl
  • H-Met-Leu-Phe-O-CH2C6H5

DownStream

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

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J. Pharmacol. Exp. Ther. 350(2) , 444-54, (2014)

Activation of mast cells and eosinophils is a fundamental process in the pathophysiology of allergic diseases. We have previously reported that the novel enhydrazinone ester CEE-1 (ethyl 4-phenylhydra...

TLR4 accessory molecule RP105 (CD180) regulates monocyte-driven arteriogenesis in a murine hind limb ischemia model.

PLoS ONE 9(6) , e99882, (2014)

We investigated the role of the TLR4-accessory molecule RP105 (CD180) in post-ischemic neovascularization, i.e. arteriogenesis and angiogenesis. TLR4-mediated activation of pro-inflammatory Ly6Chi mon...


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Related Compounds

  • FOR-MET-LEU-PHE-OH
  • FOR-MET-LEU-PHE-OH
  • For-Met-Leu-Phe-Lys-OH
  • For-Met-Leu-Phe-Phe-OH
  • For-Met-Leu-p-iodo-Phe-OH
  • For-Met-Leu-Phe-OMe
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