Linoleic acid

Suppliers

Names

[ CAS No. ]:
60-33-3

[ Name ]:
Linoleic acid

[Synonym ]:
MFCD00064241
cis,cis-9,12-octadecadienoic acid
Pamolyn
9,12-Octadecadienoic acid, (9Z,12Z)-
FEMA 3380
Hidiene
cis-9,cis-12-octadecadienoic acid
Linoleic acid
LINOLEATE
emersol310
unifac6550
EINECS 200-470-9
9-cis,12-cis-Octadecadienoic acid
IVELIP
(9Z,12Z)-9,12-Octadecadienoic acid
cis-Linoleic acid
emersol315
Linoleic
9,12-octadecadienoic acid
(9Z,12Z)-octadeca-9,12-dienoic acid

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
360.6±0.0 °C at 760 mmHg

[ Melting Point ]:
-5 °C

[ Molecular Formula ]:
C₁₈H₃₂O₂

[ Molecular Weight ]:
280.445

[ Flash Point ]:
273.0±14.4 °C

[ Exact Mass ]:
280.240234

[ PSA ]:
37.30000

[ LogP ]:
7.18

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.478

[ Storage condition ]:
2-8°C

[ Stability ]:
Stability Stable, but air and light sensitive. Combustible. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
INSOLUBLE

[ Freezing Point ]:
-5℃

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RF9990000

CHEMICAL NAME :: 9,12-Octadecadienoic acid, (Z)-

CAS REGISTRY NUMBER :: 60-33-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C18-H32-O2

MOLECULAR WEIGHT :: 280.50

WISWESSER LINE NOTATION :: QV8U3U6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Human

REFERENCE :: 85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977 Volume(issue)/page/year: -,127,1977 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >50 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,327,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >50 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3728459

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 104,793,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 43040 No. of Facilities: 4852 (estimated) No. of Industries: 61 No. of Occupations: 64 No. of Employees: 45762 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 43040 No. of Facilities: 2186 (estimated) No. of Industries: 26 No. of Occupations: 37 No. of Employees: 57612 (estimated) No. of Female Employees: 16829 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S26-S24/25-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
RF9990000

[ HS Code ]:
2916150000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Methyl linoleate
Ethyl linoleate (JAN)
trilinolein
octadeca-9,12-dienenitrile
methyl octadeca-9,12-diynoate
7-Chloroheptanoic acid
Methyl 7-chloroheptanoate
oleic acid

DownStream

N-linoleoyldopamine
9-HYDROXYNONANOIC ACID
(Z)-non-3-enoic acid
trilinolein
1-Monolinolein
1,3-dilinoleoylglycerol
1,2-Dilinoleoyl-sn-glycerol
Ethyl linoleate (JAN)
(9Z,12Z)-Octadeca-9,12-dien-1-ol
tocopheryl linoleate

Customs

[ HS Code ]: 2916190090

[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

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