Phloretin

Suppliers

Names

[ CAS No. ]:
60-82-2

[ Name ]:
Phloretin

[Synonym ]:
QR CQ EQ BV2R DQ
1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-
Dihydronaringenin
2',4',6',4-tetrahydroxydihydrochalcone
3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
β-(p-Hydroxyphenyl)phloropropiophenone
phloretol
4,2',4',6'-tetrahydroxydihydrochalcone
b-(p-Hydroxyphenyl)phloropropiophenone
UNII-S5J5OE47MK
3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
EINECS 200-488-7
Phloretin
MFCD00002288

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
534.4±29.0 °C at 760 mmHg

[ Melting Point ]:
~260 °C

[ Molecular Formula ]:
C15H14O5

[ Molecular Weight ]:
274.269

[ Flash Point ]:
291.1±20.8 °C

[ Exact Mass ]:
274.084137

[ PSA ]:
97.99000

[ LogP ]:
3.50

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.685

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Naringenin
  • Phlorizin
  • 2',4,4',6'-TETRAHYDROXYCHALCONE
  • E-3-(4-BENZYLOXY)-1-(2.4-BISBENZYLOXY-6-HYDROXY)PHENYL)PROPENONE
  • Phloroglucinol
  • Desaminotyrosine
  • 4-(Benzyloxy)benzaldehyde
  • 1-[2,4-Bis(benzyloxy)-6-hydroxyphenyl]ethanone
  • Malonyl CoA
  • Naringin dihydrochalcone

DownStream

  • 4'-Demethyl-3,9-dihydroeucomin
  • Phloroglucinol
  • Desaminotyrosine
  • 3-(4-Hydroxyphenyl)-1-propanol
  • Resorcine
  • 4-Hydroxybenzoic acid
  • 5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]chromen-4-one
  • 3-(4-acetoxy-phenyl)-1-(2,4-diacetoxy-6-hydroxy-phenyl)-propan-1-one
  • [3,5-diacetyloxy-2-[3-(4-acetyloxyphenyl)propanoyl]phenyl] acetate
  • 1-(2-hydroxy-4,6-dimethoxy-phenyl)-3-(4-methoxyphenyl)propan-1-one

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.

Oncotarget 6 , 37281-99, (2015)

Melanoma is a largely incurable skin malignancy owing to the underlying molecular and metabolic heterogeneity confounded by the development of resistance. Cancer cells have metabolic flexibility in ch...

Antagonistic control of a dual-input mammalian gene switch by food additives.

Nucleic Acids Res. 42(14) , e116, (2014)

Synthetic biology has significantly advanced the design of mammalian trigger-inducible transgene-control devices that are able to programme complex cellular behaviour. Fruit-based benzoate derivatives...

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...


More Articles

Related Compounds

  • phloretin triacetate
  • phloretin-4-D-glucoside
  • phloretin 2'-O-glucoside
  • PHLORETIN-4-METHYL ETHER
  • PHLORETIN-4-METHYL ETHER
  • Phloretin 4'-methyl ether
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine