Adenosine cyclophosphate

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Names

[ CAS No. ]:
60-92-4

[ Name ]:
Adenosine cyclophosphate

[Synonym ]:
Adenosine 3,5'-cyclic monophosphoric acid
Adenosine 3',5'-cyclic monophosphate
adenosine cyclic-monophosphate
cyclic Adenosine 3',5'-monophosphate
(4aR,6R,7R,7aS)-6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide
Cyclic AMP
3'5'-cyclic ester of AMP
adenosine-cyclic-phosphate
cyclic 3',5'-AMP
cAMP
Adenosine 3‘,5‘-cyclic monophosphate
Adenosine 3′,5′-cyclic monophosphate
adenosine cyclic 3',5'-phosphate
cyclic Adenosine 3',5'-phosphate
Cyclic 3',5'-adenylate
EINECS 200-492-9
4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, (4aR,6R,7R,7aS)-
3',5'-Cyclic AMP
Adenosine 3',5'-cyclic phosphate
3′,5′-Cyclic AMP
Adenosine-3',5'-cyclicmonophosphate
MFCD00005845
Adenosine cyclic monophosphate
Cyclic adenosine monophosphate

Chemical & Physical Properties

[ Density]:
2.5±0.1 g/cm3

[ Boiling Point ]:
701.5±70.0 °C at 760 mmHg

[ Melting Point ]:
260 °C (dec.)(lit.)

[ Molecular Formula ]:
C10H12N5O6P

[ Molecular Weight ]:
329.206

[ Flash Point ]:
378.0±35.7 °C

[ Exact Mass ]:
329.052521

[ PSA ]:
164.65000

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
2.012

[ Water Solubility ]:
50 mg/mL

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU7357600
CHEMICAL NAME :
Adenosine, cyclic 3',5'-(hydrogenphosphate)-
CAS REGISTRY NUMBER :
60-92-4
BEILSTEIN REFERENCE NO. :
0052645
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H12-N5-O6-P
MOLECULAR WEIGHT :
329.24
WISWESSER LINE NOTATION :
T56 BO FOPOTJ DQ GQ GO C- DT56 BN DN FN HNJ IZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Rodent - mouse Fibroblast
DOSE/DURATION :
500 umol/L
REFERENCE :
IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 13,404,1974

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
22-24/25-45-36/37/39-26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AU7357600

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(dichlorophosphoryloxymethyl)oxolane-3,4-diol
  • Adenosine
  • Adenosine triphosphate
  • 5'-Adenylic acid
  • equatorial-[7-(diethylamino)coumarin-4-yl]methyl adenosine cyclic 3',5'-monophosphate
  • axial-[7-(diethylamino)coumarin-4-yl]methyl adenosine cyclic 3',5'-monophosphate
  • [7-(carboxymethoxy)coumarin-4-yl]methyl ester of cAMP
  • [7-(carboxymethoxy)coumarin-4-yl]methyl ester of cAMP
  • cyclic adenosine-3',5'-monophosphate [6,7-bis(carboxymethoxy)coumarin-4-yl]methyl ester

DownStream

  • Adenosine
  • 3'-Adenylic acid
  • 5'-Adenylic acid
  • 8-bromo-Cyclic AMP
  • Adenine
  • D-ribo-3,4,5-Trihydroxy-2-phosphonooxy-valeraldehyd
  • D-ribo-2,4,5-Trihydroxy-3-phosphonooxy-valeraldehyd
  • Adenosine triphosphate
  • INOSINE-3',5'-CYCLIC PHOSPHATE
  • 6-bn-camp sodium salt

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J. Neurosci. 34(20) , 6910-23, (2014)

Exaggerated intracellular Ca(2+) signaling is a robust proximal phenotype observed in cells expressing familial Alzheimer's disease (FAD)-causing mutant presenilins (PSs). The mechanisms that underlie...


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Related Compounds

  • adenosine cyclophosphate
  • Adenosine,5'-(3-pyridinecarboxylate) (9CI)
  • Adenosine 5'-(trihydrogen diphosphate), 2'-deoxy-, 3'-[2-(methylamino)benzoate]
  • Adenosine-5''-O-(1-thiotriphosphoric acid), Rp-isomer
  • Adenosine,2,3-dihydro-N-methyl-2-oxo-
  • Adenosine, cyclic2',3'-(hydrogen phosphate), monosodium salt (9CI)
  • 1-Cyanocyclobutane-1-sulfonamide
  • 2-Fluoro-2-phenylethane-1-sulfonamide
  • 4-(1-Isocyanatoethyl)heptane
  • 3-hydroxy-3-(1H-1,2,4-triazol-3-yl)propanoic acid
  • 2-(1-Cycloheptylcyclobutyl)acetic acid
  • 1-(Benzylamino)-4-chloropent-4-en-2-one
  • 8-Ethyl-4,4-difluoro-2-azaspiro[4.5]decane
  • 4-(But-3-yn-2-yl)-1,1-dimethylcyclohexane
  • Methyl 3-(1-azido-2-hydroxyethyl)benzoate
  • 3-(Cyclopropylmethyl)-2,2-dimethylmorpholine
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