2-Oxobutyric acid

Suppliers

Names

[ CAS No. ]:
600-18-0

[ Name ]:
2-Oxobutyric acid

[Synonym ]:
Butanoic acid, 2-oxo-
EINECS 209-986-9
α-oxobutyric acid
2-oxo-Butyric acid
a-keto-n-butyric acid
MFCD00004164
methyl-Pyruvic acid
propionyl- Formic acid
a-Oxobutyric acid
2-Oxobutyric acid
a-oxo-n-butyric acid
2-Oxobutanoic acid
a-ketobutyric acid

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
177.8±0.0 °C at 760 mmHg

[ Melting Point ]:
30-34 °C(lit.)

[ Molecular Formula ]:
C₄H₆O₃

[ Molecular Weight ]:
102.089

[ Flash Point ]:
65.0±15.2 °C

[ Exact Mass ]:
102.031693

[ PSA ]:
54.37000

[ LogP ]:
-0.71

[ Vapour Pressure ]:
0.5±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.427

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
1759

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(R)-2-HYDROXYBUTYRIC ACID
2-Butynoic acid
2-Ketoglutaric acid
H-D-Abu-OH
1-Aminocyclopropane-1-carboxylic acid
(Z)-2-methoxy-2-butenoic acid
(±)-2-hydroxybutyric acid
2-oxalopropionic acid

DownStream

Methyl 2-oxobutanoate
(S)-2-Hydroxybutyric acid
L(+)-2-Aminobutyric acid
Phenyl ethyl ketone
Benzeneacetic acid, a-hydroxy-a-methyl-
2',5'-dihydroxypropiophenone
H-D-Abu-OH
Pyruvic acid
Methyl propanoate
2-Aminobutanoic acid

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Mosquito odorant receptor for DEET and methyl jasmonate.

Proc. Natl. Acad. Sci. U. S. A. 111(46) , 16592-7, (2014)

Insect repellents are important prophylactic tools for travelers and populations living in endemic areas of malaria, dengue, encephalitis, and other vector-borne diseases. DEET (N,N-diethyl-3-methylbe...

Kinetic resolution of 2-hydroxybutanoate racemic mixtures by NAD-independent L-lactate dehydrogenase.

Bioresour. Technol. 102(7) , 4595-9, (2011)

Optically active D-2-hydroxybutanoate is an important building block intermediate for medicines and biodegradable poly(2-hydroxybutanoate). Kinetic resolution of racemic 2-hydroxybutanoate may be a gr...

Transaminase-catalyzed asymmetric synthesis of L-2-aminobutyric acid from achiral reactants.

Biotechnol. Lett. 31 , 1595-1599, (2009)

Asymmetric synthesis of an unnatural amino acid was demonstrated by omega-transaminase from Vibrio fluvialis JS17. L-2-Aminobutyric acid was synthesized from 2-oxobutyric acid and benzylamine with an ...