N-Hydroxysuccinimide

Suppliers

Names

[ Name ]:
N-Hydroxysuccinimide

[Synonym ]:
1-Hydroxy-2,5-pyrrolidinedione
N-hydroxy-succinimide
HOSu
N-Hydroxysuccinimide
2,5-Pyrrolidinedione, 1-hydroxy-
hydroxysuccinimide
succinimide, N-hydroxy-
N-hydroxyl succinimide
1-hydroxypyrrolidine-2,5-dione
1-Hydroxy-pyrrolidine-2,5-dione
Succinimide, N-hydroxy- (8CI)
MFCD00005516
EINECS 228-001-3

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
262.4±23.0 °C at 760 mmHg

[ Melting Point ]:
95-98 °C(lit.)

[ Molecular Formula ]:
C₄H₅NO₃

[ Molecular Weight ]:
115.087

[ Flash Point ]:
112.5±22.6 °C

[ Exact Mass ]:
115.026939

[ PSA ]:
57.61000

[ LogP ]:
-2.00

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.600

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, strong bases. Protect from moisture.

[ Water Solubility ]:
SOLUBLE

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Succinic acid
tert-butyl 2,5-dioxopyrrolidine-1-carboxylate
Glutaric acid
N-succinimidyl benzoate
1,3-Diaminopropane
Diethyl succinate
Succinic anhydride
hydroxylamine succinic acid salt
acetic acid
4-methoxybenzoic acid 2,5-dioxo-1-pyrrolidinyl ester

DownStream

(2,5-dioxopyrrolidin-1-yl) 2-fluorobenzoate
(2,5-dioxopyrrolidin-1-yl) 3-methylsulfanylpropanoate
Nonanedioic acid 1,9-bis(2,5-dioxo-1-pyrrolidinyl) ester
(2,5-dioxopyrrolidin-1-yl) 4-(2-methoxy-4-nitrophenoxy)butanoate
SUCCINIMIDYL-5-(BROMOACETAMIDO)PENTANOATE
2,5-Dioxopyrrolidin-1-yl heptanoate
(2,5-dioxopyrrolidin-1-yl) 1,2,2,2-tetrachloroethyl carbonate
2,5-Dioxopyrrolidin-1-yl nonanoate
pht-gly-osu
N-acryloxysuccinimide

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

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Natural biomolecules are often used to functionalize materials to achieve desired cell-material interactions. However, their applications can be limited owing to denaturation during the material funct...

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N-HYDROXYSUCCINIMIDE
N-hydroxysuccinimide*NH3
sulfo-N-hydroxysuccinimide
N-hydroxysuccinimide-biotin
N-hydroxysuccinimide biotin
N-hydroxysuccinimide-biotin
2-[3'-(3,4-Dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide
N-(4-chlorophenyl)-2-(3'-(3,4-dimethylphenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide
2-(3'-(3,4-difluorophenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)-N-(2,5-dimethylphenyl)acetamide
N-(3,5-dimethylphenyl)-2-(3'-(4-fluorophenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide
2-{4,6-dioxo-5-[4-(propan-2-yl)phenyl]-1H,3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2,3]triazol-1-yl}-N-phenylacetamide
N-(3-chlorophenyl)-2-{4,6-dioxo-5-[4-(propan-2-yl)phenyl]-1H,3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2,3]triazol-1-yl}acetamide
N-(2,3-dimethylphenyl)-2-[5-(4-isopropylphenyl)-4,6-dioxo-4,5,6,6a-tetrahydropyrrolo[3,4-d][1,2,3]triazol-1(3aH)-yl]acetamide
2-[5-(3-chloro-4-methoxyphenyl)-4,6-dioxo-4,5,6,6a-tetrahydropyrrolo[3,4-d][1,2,3]triazol-1(3aH)-yl]-N-phenylacetamide
2-[5-(3-chloro-4-methoxyphenyl)-4,6-dioxo-4,5,6,6a-tetrahydropyrrolo[3,4-d][1,2,3]triazol-1(3aH)-yl]-N-(4-methylphenyl)acetamide
2-[5-(3-chloro-4-methoxyphenyl)-4,6-dioxo-4,5,6,6a-tetrahydropyrrolo[3,4-d][1,2,3]triazol-1(3aH)-yl]-N-(2-fluorophenyl)acetamide

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