tectoridin

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Names

[ CAS No. ]:
611-40-5

[ Name ]:
tectoridin

[Synonym ]:
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-
Tectorigenin 7-glucoside
4',5-Dihydro-6-methoxy-7-(o-glucoside)isoflavone
5-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4-oxo-4H-chromen-7-yl β-D-glucopyranoside
Shekanin
tectoridin
Tectoridin (7CI,8CI)
5-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
798.1±60.0 °C at 760 mmHg

[ Melting Point ]:
261.8-263.2ºC

[ Molecular Formula ]:
C22H22O11

[ Molecular Weight ]:
462.404

[ Flash Point ]:
279.7±26.4 °C

[ Exact Mass ]:
462.116211

[ PSA ]:
179.28000

[ LogP ]:
0.29

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.695

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ3090000
CHEMICAL NAME :
4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyph enyl)-6-methoxy-
CAS REGISTRY NUMBER :
611-40-5
BEILSTEIN REFERENCE NO. :
0068384
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H22-O11
MOLECULAR WEIGHT :
462.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4200 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 64,186,1968

Safety Information

[ Hazard Codes ]:
C

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DJ3090000

[ HS Code ]:
29389090

Precursor & DownStream

Precursor

DownStream

  • Irisolidone

Articles

Tectorigenin inhibits IFN-gamma/LPS-induced inflammatory responses in murine macrophage RAW 264.7 cells.

Arch. Pharm. Res. 31(11) , 1447-56, (2008)

Tectorigenin (Tg) and tectoridin (Td) are the major compounds isolated from the rhizomes of iridaceous plant Belamcanda chinensis which is well known as a chinese traditional medicine for the treatmen...

Tectoridin, a poor ligand of estrogen receptor alpha, exerts its estrogenic effects via an ERK-dependent pathway.

Mol. Cells 27(3) , 351-7, (2009)

Phytoestrogens are the natural compounds isolated from plants, which are structurally similar to animal estrogen, 17beta-estradiol. Tectoridin, a major isoflavone isolated from the rhizome of Belamcan...

Microbial transformation and bioactivation of isoflavones from Pueraria flowers by human intestinal bacterial strains.

J. Nat. Med. 63(3) , 254-60, (2009)

The flowers from Pueraria, which are called Puerariae Flos, have been used since ancient times for recovery from alcohol intoxication. We elucidated the microbial transformation of the main isoflavone...


More Articles

Related Compounds

  • 1-(5-(Cyclopropylmethoxy)pyridin-2-yl)ethanone
  • 2-(4-Bromo-3-fluorophenyl)oxirane
  • 1-(4-Bromo-3-fluorophenyl)-2-(methylamino)ethan-1-ol
  • 3-Ethoxy-1-(5-fluoropyridin-2-yl)prop-2-en-1-one
  • 1-[5-(4-Chloro-1H-pyrazol-1-yl)pyridin-2-yl]ethan-1-one
  • 1-[5-(4-Bromo-1H-pyrazol-1-yl)pyridin-2-yl]ethan-1-one
  • 3-(4-Bromo-3-fluorophenyl)prop-2-en-1-amine
  • 1-(5-Fluoropyridin-2-yl)-3,3-dimethoxypropan-1-one
  • 3-(4-Bromo-3-fluorophenyl)prop-2-en-1-ol
  • 5-Chloro-3-phenyl-1,2,4-triazolo[4,3-a]pyrazine