Quinine Hydrochloride Dihydrate

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Names

[ Name ]:
Quinine Hydrochloride Dihydrate

[Synonym ]:
Quinine hydrochloride,(R)-(6-Methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanolhydrochloride
EINECS 231-437-7
MFCD00151248
Quinine monohydrochloride dihydrate
Quinine Hydrochloride Dihydrate
Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-, hydrochloride, hydrate (1:1:2)
(8α,9R)-6'-Methoxycinchonan-9-ol hydrochloride dihydrate
Quinine (hydrochloride dihydrate)

Chemical & Physical Properties

[ Boiling Point ]:
633ºC at 760 mmHg

[ Melting Point ]:
115-116 °C (dec.)(lit.)

[ Molecular Formula ]:
C₂₀H₂₉ClN₂O₄

[ Molecular Weight ]:
396.908

[ Flash Point ]:
122 °C

[ Exact Mass ]:
396.181580

[ PSA ]:
64.05000

[ LogP ]:
3.78450

[ Index of Refraction ]:
-250 ° (C=2, EtOH)

[ Storage condition ]:
Store at -20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H317-H334

[ Precautionary Statements ]:
P261-P280-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S22-S36/37-S45-S36/37/39-S26

[ RIDADR ]:
1544

[ WGK Germany ]:
3

[ RTECS ]:
VA7700000

[ HS Code ]:
29392000

Precursor & DownStream

Precursor

DownStream

6-Methoxy-4-quinolinecarbaldehyde
2-(dimethoxymethyl)-5-vinylquinuclidine
7'-(1,3-dimethoxycarbonyl-2-hydroxyprop-2-yl)-deoxyquinine
trimethyl 2,2',2''-(3-hydroxy-6-(hydroxy(5-vinylquinuclidin-2-yl)methyl)-8-methoxy-1-oxo-2,3,5,6-tetrahydro-1H-3a,6-methanobenzo[d]pyrrolo[2,1-b][1,3]oxazepine-3,5,5-triyl)triacetate
5-ethenyl-1-azabicyclo[2.2.2]octane-2-carbaldehyde

Customs

[ HS Code ]: 29392000

Articles

Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A.

J. Pharm. Biomed. Anal. 30(4) , 1287-96, (2002)

NAMI-A is a novel ruthenium complex with selective activity against metastases currently in Phase I clinical trials in The Netherlands. The photostability of this new agent in solid state and in solut...

Quinine blocks a calcium-activated potassium conductance in mammalian enteric neurones.

Br. J. Pharmacol. 83(1) , 3-5, (1984)

Quinine (100 microM) abolished the slow calcium-dependent afterhyperpolarization which occurs after an action potential in some neurones of the guinea-pig myenteric and submucous plexus. This occurred...

Treatment of severe malaria.

J. R. Soc. Med. 82 Suppl 17 , 44-50; discussion 50-1, (1989)

In the treatment of severe Plasmodium falciparum infection antimalarial drugs should, ideally, be given by controlled rate intravenous infusion until the patient is able to swallow tablets. In cases w...

quinine hydrochloride dihydrate
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2-(Difluoromethyl)-3-nitrobenzoic acid
5-{[(Tert-butoxy)carbonyl]amino}-4-chloro-1,2-oxazole-3-carboxylic acid
tert-butyl (2S,3S)-2-isopropylpyrrolidine-3-carboxylate
Methyl 2-(2,5-difluoroanilino)pyridine-3-carboxylate
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Tert-butyl 2-amino-3-fluoro-6-methoxybenzoate
Tert-butyl 2-amino-3-fluoro-4-methoxybenzoate
Tert-butyl 4-(methylamino)-3-nitrobenzoate
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