Chloroquinoline

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
267.3±13.0 °C at 760 mmHg

[ Melting Point ]:
34-37 °C(lit.)

[ Molecular Formula ]:
C₉H₆ClN

[ Molecular Weight ]:
163.604

[ Flash Point ]:
141.2±5.4 °C

[ Exact Mass ]:
163.018875

[ PSA ]:
12.89000

[ LogP ]:
2.71

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.652

[ Water Solubility ]:
Insoluble

Click to get detail MSDS

CHEMICAL IDENTIFICATION

RTECS NUMBER :

VB2320000

CHEMICAL NAME :

Quinoline, 2-chloro-

CAS REGISTRY NUMBER :

612-62-4

BEILSTEIN REFERENCE NO. :

0112561

LAST UPDATED :

199701

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VB2320000

[ HS Code ]:
2933499090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Antiprotozoal activity of chloroquinoline based chalcones.

Eur. J. Med. Chem. 46 , 1897-905, (2011)

A new series of chloroquinoline based chalcones were synthesized and evaluated for in vitro antiamoebic and antimalarial activities. The results showed that out of fifteen compounds, four were found t...

Ruthenium-catalyzed cyclization of anilides with substituted propiolates or acrylates: an efficient route to 2-quinolinones.

Org. Lett. 16(13) , 3568-71, (2014)

A Ru-catalyzed cyclization of anilides with propiolates or acrylates affording 2-quinolinones having diverse functional groups in good to excellent yields is described. Later, 2-quinolinones were conv...

Chemoenzymatic synthesis of chiral 2,2'-bipyridine ligands and their N-oxide derivatives: applications in the asymmetric aminolysis of epoxides and asymmetric allylation of aldehydes.

Org. Biomol. Chem. 8(5) , 1081-90, (2010)

A series of enantiopure 2,2'-bipyridines have been synthesised from the corresponding cis-dihydrodiol metabolites of 2-chloroquinolines. Several of the resulting hydroxylated 2,2'-bipyridines were fou...

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