1-Boc-4-Fluoro-4-(hydroxymethyl)piperidine

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Names

[ CAS No. ]:
614730-97-1

[ Name ]:
1-Boc-4-Fluoro-4-(hydroxymethyl)piperidine

[Synonym ]:
tert-butyl 4-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
311.0±27.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H20FNO3

[ Molecular Weight ]:
233.280

[ Flash Point ]:
141.9±23.7 °C

[ Exact Mass ]:
233.142715

[ PSA ]:
49.77000

[ LogP ]:
0.86

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.481

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • tert-Butyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate
  • Ethyl N-Boc-4-fluoropiperidine-4-carboxylate

DownStream

  • TERT-BUTYL-4-AMINOMETHYL-4-FLUOROPIPERIDINE-1-CARBOXYLATE
  • tert-butyl 4-fluoro-4-(methylsulfonyloxymethyl)piperidine-1-carboxylate
  • 1-Boc-4-fluoro-4-formylpiperidine
  • tert-butyl 4-[(1,3-dioxoisoindol-2-yl)methyl]-4-fluoropiperidine-1-carboxylate

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 1-Boc-4-[(4-chlorophenyl)hydroxyMethyl]piperidine
  • 1-BOC-4-ETHYL-4-(HYDROXYMETHYL)-PIPERIDINE
  • 1-Boc-4-fluoro-4-formylpiperidine
  • 1-boc-4-[(3-methylphenyl)methyl]-4-(hydroxymethyl)-piperidine
  • 1-BOC-4-[(2-METHYLPHENYL)METHYL]-4-(HYDROXYMETHYL)-PIPERIDINE
  • 1-BOC-4-[[3-(TRIFLUOROMETHOXY)PHENYL]METHYL]-4-(HYDROXYMETHYL)-PIPERIDINE