Ethyl acetopyruvate

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Names

[ CAS No. ]:
615-79-2

[ Name ]:
Ethyl acetopyruvate

[Synonym ]:
Ethyl acetopyruvate
EINECS 210-447-5
Ethyl 2,4-dioxovalerate
Ethyl 2,4-dioxopentanoate
Pentanoic acid, 2,4-dioxo-, ethyl ester
MFCD00009124

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
214.7±13.0 °C at 760 mmHg

[ Melting Point ]:
16-18 °C(lit.)

[ Molecular Formula ]:
C7H10O4

[ Molecular Weight ]:
158.152

[ Flash Point ]:
85.8±19.9 °C

[ Exact Mass ]:
158.057907

[ PSA ]:
60.44000

[ LogP ]:
-0.19

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.426

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29183000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Diethyloxalate
  • Acetone
  • Triethyl orthoformate
  • acrylic acid methyl ester
  • 2-Cyanoacetamide
  • Sodium ethoxide
  • benzene

DownStream

  • Ethyl 3-cyano-2-mercapto-6-methylisonicotinate
  • Ethyl 3-chloro-2,4-dioxopentanoate
  • Ethyl 1,5-dimethyl-1H-pyrazole-3-carboxylate
  • Ethyl 1,3-dimethylpyrazole-5-carboxylate
  • Ethyl 5-methyl-1,2-oxazole-3-carboxylate
  • ethyl 3-methyl-1,2-oxazole-5-carboxylate
  • (5-methylisoxazol-3-yl)methanol
  • 1,5-Dimethyl-1H-pyrazole-3-carboxylic acid
  • 1,3-Dimethyl-1H-pyrazole-5-carboxylic acid
  • 5-Methylisoxazole-3-carboxylic acid

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

New one pot synthesis of a chiral a-hydroxy-?-butyrolactone via sequential asymmetric hydrogenation of an a, ?-diketoester. Blandin V, et al.

Tetrahedron Asymmetry 9(16) , 2765-2768, (1998)

Preparation of 1-(4-methoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective and bioavailable inhibitors of coagulation factor Xa.

Bioorg. Med. Chem. Lett. 16 , 3755, (2006)

Previously, potent factor Xa inhibitors were described based on a pyrazole core. Modifications of the pyrazole core have provided additional novel, highly potent factor Xa inhibitors. This manuscript ...

Identification of novel pyrazole acid antagonists for the EP1 receptor.

Bioorg. Med. Chem. Lett. 16 , 4767, (2006)

The discovery, synthesis and structure-activity relationship (SAR) of a novel series of EP1 receptor antagonists is described. Pyrazole acid 4, identified from a chemical array, had desirable physicoc...


More Articles

Related Compounds

  • ethyl 8-(4-fluorophenyl)-8-oxooctanoate
  • ETHYL 4-(3,4-DIMETHYLPHENYL)-4-OXOBUTYRATE
  • ethyl 3-(3-nitrophenyl)-4-oxopent-2-enoate
  • ETHYL 8-(1-NAPHTHYL)-8-OXOOCTANOATE
  • ETHYL 2-((TERT-BUTOXYCARBONYL)AMINO)THIAZOLE-5-CARBOXYLATE
  • ETHYL MORPHOLINE-2-CARBOXYLATE HYDROCHLORIDE