Ethyl acetopyruvate

Ethyl acetopyruvate Structure
Ethyl acetopyruvate structure
Common Name Ethyl acetopyruvate
CAS Number 615-79-2 Molecular Weight 158.152
Density 1.1±0.1 g/cm3 Boiling Point 214.7±13.0 °C at 760 mmHg
Molecular Formula C7H10O4 Melting Point 16-18 °C(lit.)
MSDS Chinese USA Flash Point 85.8±19.9 °C

New one pot synthesis of a chiral a-hydroxy-?-butyrolactone via sequential asymmetric hydrogenation of an a, ?-diketoester. Blandin V, et al.

Tetrahedron Asymmetry 9(16) , 2765-2768, (1998)

Preparation of 1-(4-methoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective and bioavailable inhibitors of coagulation factor Xa.

Bioorg. Med. Chem. Lett. 16 , 3755, (2006)

Previously, potent factor Xa inhibitors were described based on a pyrazole core. Modifications of the pyrazole core have provided additional novel, highly potent factor Xa inhibitors. This manuscript will describe the synthesis and biological activity of fact...

Identification of novel pyrazole acid antagonists for the EP1 receptor.

Bioorg. Med. Chem. Lett. 16 , 4767, (2006)

The discovery, synthesis and structure-activity relationship (SAR) of a novel series of EP1 receptor antagonists is described. Pyrazole acid 4, identified from a chemical array, had desirable physicochemical properties, an excellent in vitro microsomal inhibi...

Acylpyruvates as potential antifungal agents.

J. Med. Chem. 15(4) , 429-31, (1972)