2-trimethylsilyloxyfuran

Names

[ Name ]:
2-trimethylsilyloxyfuran

[Synonym ]:
2-(Trimethylsilyloxy)furan
furan-2-yloxy(trimethyl)silane
2-trimethylsilyloxyfuran
Silane, (2-furanyloxy)trimethyl-
(2-Furyloxy)(trimethyl)silane
MFCD00011729

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
148.6±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₁₂O₂Si

[ Molecular Weight ]:
156.255

[ Flash Point ]:
24.4±0.0 °C

[ Exact Mass ]:
156.060654

[ PSA ]:
22.37000

[ LogP ]:
-1.16

[ Vapour Pressure ]:
5.3±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.437

[ Storage condition ]:
−20°C

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F: Flammable;Xi: Irritant;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S26

[ RIDADR ]:
UN 1993 3/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2932190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Chlorotrimethylsilane
2(5H)-Furanone
Trimethylsilyl trifluoromethanesulfonate
Furfuryl alcohol
Hexamethyldisilazane
furan-2-yl-lithium
Dioxybis(trimethylsilane)
N,N-Diethyl-1,1,1-trimethylsilanamine

DownStream

Acetic acid,2,2,2-trifluoro-, butyl ester
2(5H)-Furanone
3-butylfuran-2(3H)-one
butyl 4-oxooctanoate
Ethyl 4-Oxohexanoate
2-hexen-4-olide
2(3H)-Furanone,5-(4-methylphenyl)-
5-ETHOXYFURAN-2(5H)-ONE
tert-butyl (4S)-4-[(S)-hydroxy-[(2S)-5-oxo-2H-furan-2-yl]methyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Simple diastereoselectivity of the BF3.OEt2-catalyzed vinylogous Mukaiyama aldol reaction of 2-(trimethylsiloxy)furans with aldehydes.

J. Org. Chem. 70(9) , 3654-9, (2005)

[reaction: see text] A comprehensive scan of the transition state space for the reaction of 2-(trimethylsiloxy)furan and methacrolein (24 combinations) offered a satisfactory explanation of the high l...

Nucleophilic addition reaction of 2-trimethylsilyloxyfuran to N-gulosyl-C-alkoxymethylnitrones: synthetic approach to polyoxin C.

Org. Lett. 4 , 1111, (2002)

[reaction: see text] The stereoselectivity of nucleophilic addition of 2-trimethylsilyloxyfuran to N-gulosyl-C-alkoxymethylnitrones was investigated. It was found that the selectivity was highly depen...

G. Desimoni et al.

Tetrahedron 57 , 10203, (2001)

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2-methyl-2-methylsulfanylpropanenitrile
2-(4-methoxyphenyl)-4-nitrobenzoic acid
2-(4-methoxyphenyl)-5-methylbenzoic acid
2-(4-methoxyphenyl)-6-methylbenzoic acid
2-(4-methylphenyl)-4-nitrobenzoic acid
4-[4-(Piperidin-3-yloxy)but-2-yn-1-yl]morpholine
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
tert-butyl N-[2-amino-2-(2-methoxy-3-methylphenyl)ethyl]carbamate
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine