cis-4-hydroxy-L-proline

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Names

[ CAS No. ]:
618-27-9

[ Name ]:
cis-4-hydroxy-L-proline

[Synonym ]:
D-Proline, 4-hydroxy-, (4R)-
(2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid
cis-4-Hydroxy-L-proline
(4R)-4-Hydroxy-D-proline
cis-4-Hydroxyproline
MFCD00064319
(4S)-4-Hydroxy-L-prolin
cis-4-Hydroxy-D-proline
EINECS 210-542-1

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
355.2±42.0 °C at 760 mmHg

[ Melting Point ]:
257ºC

[ Molecular Formula ]:
C5H9NO3

[ Molecular Weight ]:
131.130

[ Flash Point ]:
168.6±27.9 °C

[ Exact Mass ]:
131.058243

[ PSA ]:
69.56000

[ LogP ]:
-1.84

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.540

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • (4S)-1-[(Benzyloxy)carbonyl]-4-hydroxy-L-proline
  • (2S,4S)-DIBENZYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE
  • Proline
  • L-Hydroxyproline
  • Z-Hyp-OH
  • (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2S,4S)-4-(benzoyloxy)pyrrolidine-2-carboxylate
  • (S)-2-(((S)-1-phenylethyl)amino)pent-4-enamide
  • (3S,5S)-5-(iodomethyl)-3-(((S)-1-phenylethyl)amino)dihydrofuran-2(3H)-one
  • (2S,4R)-DIBENZYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE
  • N-BOC-cis-4-Hydroxy-L-proline

DownStream

  • L-ERYTHRO-4-FLUORO-GLUTAMIC ACID
  • Fomc-cis-L-hydroxyproline-OH
  • N-BOC-cis-4-Hydroxy-L-proline
  • (2S,4S)-4-FLUOROPYRROLIDINE-2-CARBOXYLIC ACID
  • (4S)-1-[(Benzyloxy)carbonyl]-4-hydroxy-L-proline
  • Proline,1-(2,4-dinitrophenyl)-4-hydroxy-, L- (8CI)
  • L-Proline, 4-hydroxy-, methyl ester, (4S)- (9CI)
  • (2S,4S)-BENZYL 4-HYDROXY-2-(HYDROXYMETHYL)PYRROLIDINE-1-CARBOXYLATE

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • N-BOC-cis-4-Hydroxy-L-proline
  • N-fmoc-cis-4-hydroxy-L-proline
  • 1-Methyl-cis-4-hydroxy-L-proline
  • cis-4-hydroxy-L-proline methylester
  • cis-4-hydroxy-L-proline methyl ester
  • cis-4-hydroxy-L-proline methyl ester
  • 1-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidine-4-carboxylic acid
  • 1-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-2,2-diphenylethanone
  • 2-(9-Methyl-3,5-diphenyl-7H-furo[3,2-g][1]benzopyran-7-ylidene)-N-2-propen-1-ylhydrazinecarbothioamide
  • 2-[3-(4-Chlorophenyl)-5-phenyl-7H-furo[3,2-g][1]benzopyran-7-ylidene]-N-(1-methylethyl)hydrazinecarbothioamide
  • 1-(6-Acetyl-1,2,3,4-tetrahydroquinolin-1-yl)-2-chloroethan-1-one
  • 6-Morpholin-4-ylpyrimidine-4-thiol
  • tert-Butyl 4-(2-(cyclopropylamino)-2-oxoethyl)piperazine-1-carboxylate
  • 2-(propan-2-yl)-N-(pyridin-2-ylmethyl)quinoline-4-carboxamide
  • 1,3,4-Oxadiazole, 2-(2-ethoxyphenyl)-5-phenyl-
  • 3-piperidin-4-yl-6-(trifluoromethoxy)-1H-indole
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