(+/-)-4-Hydroxy Mephenytoin

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Names

[ CAS No. ]:
61837-65-8

[ Name ]:
(+/-)-4-Hydroxy Mephenytoin

[Synonym ]:
4-hydroxy mephenytoin
5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione
5-Ethyl-5-(4-hydroxyphenyl)-3-methylimidazolidine-2,4-dione
2,4-Imidazolidinedione, 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-
4-Hydroxymephenytoin

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
153-154ºC

[ Molecular Formula ]:
C12H14N2O3

[ Molecular Weight ]:
234.251

[ Exact Mass ]:
234.100449

[ PSA ]:
69.64000

[ LogP ]:
0.66

[ Index of Refraction ]:
1.568

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol

Articles

The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet.

Biochem. Pharmacol. 93(3) , 389-400, (2015)

There is an unmet medical need for novel NAFLD treatments. Here we have examined the effects of liver-selective NO donor (V-PYRRO/NO) as compared with metformin on hepatic steatosis and glucose tolera...

Size- and time-dependent alteration in metabolic activities of human hepatic cytochrome P450 isozymes by gold nanoparticles via microsomal coincubations.

Nanoscale Res. Lett. 9(1) , 642, (2014)

Nano-sized particles are known to interfere with drug-metabolizing cytochrome P450 (CYP) enzymes, which can be anticipated to be a potential source of unintended adverse reactions, but the mechanisms ...

Quantification of mephenytoin and its metabolites 4'-hydroxymephenytoin and nirvanol in human urine using a simple sample processing method.

Rapid Commun. Mass Spectrom. 18(15) , 1675-80, (2004)

A reliable and easy to use liquid chromatography/tandem mass spectrometry (LC/MS/MS) method without the use of sample extraction was developed for the simultaneous quantification of urinary concentrat...


More Articles


Related Compounds

  • (+/-)-4-Hydroxy Mephenytoin-d3
  • (+-)-4-hydroxy-4,8-dimethyl-6-oxo-nonanoic acid-lactone
  • (+)-4-Hydroxy-6'-methoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester
  • (+/-)-4-hydroxy-6-hepten-2-one
  • (+/-)-4-hydroxy-2-methyl-2.4-di-p-tolyl-pentane
  • (+/-)-4-Hydroxy-1-(1.3-dimethyl-butyl)-benzol
  • Methyl 2-(2-acetyl-4-chlorophenoxy)propanoate
  • 2-[4-(Hydroxymethyl)phenoxy]propanenitrile
  • 2-(4-Iodophenoxy)pyrazine
  • Ethyl 1-(3-nitropyridin-2-yl)piperidine-4-carboxylate
  • N-(3-chlorobenzyl)pyrimidin-2-amine
  • 3-(3-Hydroxypiperidin-1-yl)benzo[d]isothiazole 1,1-dioxide
  • 3,5-dimethyl-4-[(E)-2-nitroethenyl]-1,2-oxazole
  • 3-{[(2-bromophenyl)methyl]sulfanyl}-4-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one
  • 3-Piperidinamine, N-[2-(4-chlorophenoxy)ethyl]-N-methyl-
  • 6-((((9h-Fluoren-9-yl)methoxy)carbonyl)amino)picolinic acid
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