(+/-)-4-Hydroxy Mephenytoin

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Names

[ CAS No. ]:
61837-65-8

[ Name ]:
(+/-)-4-Hydroxy Mephenytoin

[Synonym ]:
4-hydroxy mephenytoin
5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione
5-Ethyl-5-(4-hydroxyphenyl)-3-methylimidazolidine-2,4-dione
2,4-Imidazolidinedione, 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-
4-Hydroxymephenytoin

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
153-154ºC

[ Molecular Formula ]:
C12H14N2O3

[ Molecular Weight ]:
234.251

[ Exact Mass ]:
234.100449

[ PSA ]:
69.64000

[ LogP ]:
0.66

[ Index of Refraction ]:
1.568

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol

Articles

The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet.

Biochem. Pharmacol. 93(3) , 389-400, (2015)

There is an unmet medical need for novel NAFLD treatments. Here we have examined the effects of liver-selective NO donor (V-PYRRO/NO) as compared with metformin on hepatic steatosis and glucose tolera...

Size- and time-dependent alteration in metabolic activities of human hepatic cytochrome P450 isozymes by gold nanoparticles via microsomal coincubations.

Nanoscale Res. Lett. 9(1) , 642, (2014)

Nano-sized particles are known to interfere with drug-metabolizing cytochrome P450 (CYP) enzymes, which can be anticipated to be a potential source of unintended adverse reactions, but the mechanisms ...

Quantification of mephenytoin and its metabolites 4'-hydroxymephenytoin and nirvanol in human urine using a simple sample processing method.

Rapid Commun. Mass Spectrom. 18(15) , 1675-80, (2004)

A reliable and easy to use liquid chromatography/tandem mass spectrometry (LC/MS/MS) method without the use of sample extraction was developed for the simultaneous quantification of urinary concentrat...


More Articles


Related Compounds

  • (+/-)-4-Hydroxy Mephenytoin-d3
  • (+-)-4-hydroxy-4,8-dimethyl-6-oxo-nonanoic acid-lactone
  • (+)-4-Hydroxy-6'-methoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester
  • (+/-)-4-hydroxy-6-hepten-2-one
  • (+/-)-4-hydroxy-2-methyl-2.4-di-p-tolyl-pentane
  • (+/-)-4-Hydroxy-1-(1.3-dimethyl-butyl)-benzol
  • 2-(Azetidin-3-yl)-6-methoxyphenol
  • 5-(Azetidin-3-yl)pyridin-3-ol
  • 2-Chloro-3-(piperidin-3-yl)pyridine
  • 3-Pyridinol, 4-(aminomethyl)-5-fluoro-
  • 6-Cyclopropyl-5-methyl-3-pyridinecarboxylic acid
  • 3-(Difluoromethyl)-1H-pyrrolo[2,3-b]pyridine
  • 3-(Difluoromethoxy)-2-methylbenzonitrile
  • 2-Methyl-1,8-naphthyridin-3-amine
  • 2,6-difluoro-N-{[1-(pyridin-4-yl)piperidin-4-yl]methyl}benzene-1-sulfonamide
  • 1-(Thiazol-5-YL)cyclopropane-1-carbonitrile
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