poly-l-histidine

Suppliers

Names

[ CAS No. ]:
61857-39-4

[ Name ]:
poly-l-histidine

[Synonym ]:
DL-Histidin, Dihydrochlorid
POLY-L-HISTIDINE

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₁₀ClN₃O₂

[ Molecular Weight ]:
191.61500

[ Exact Mass ]:
191.04600

[ PSA ]:
92.00000

[ LogP ]:
0.86640

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

pH-sensitive cationic polymer gene delivery vehicle: N-Ac-poly(L-histidine)-graft-poly(L-lysine) comb shaped polymer.

Bioconjug. Chem. 11 , 637-645, (2000)

Advancing biotechnology spurs the development of new pharmaceutically engineered gene delivery vehicles. Poly(L-histidine) ¿PLH¿ has been shown to induce membrane fusion at endosomal pH values, wherea...

Dispersion of multi-wall carbon nanotubes in polyhistidine: Characterization and analytical applications

Anal. Chim. Acta 710 , 58-64, (2012)

Graphical abstract

Carboxymethyl poly(L-histidine) as a new pH-sensitive polypeptide to enhance polyplex gene delivery. Asayama S, Sudo M, et al.

Mol. Pharmacol. 5 , 898-901, (2008)

Poly-L-histidine
poly(1-benzylhistidine)
poly(l-lactide)
N-Fmoc-1,6-hexanediamine hydrobromide
poly-L-alanine
poly-l-methionine
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
4-Piperidinol, 1-[4-[(2-hydroxyphenyl)methyl]phenyl]-, 4-acetate
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide