poly-l-histidine

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Names

[ CAS No. ]:
61857-39-4

[ Name ]:
poly-l-histidine

[Synonym ]:
DL-Histidin, Dihydrochlorid
POLY-L-HISTIDINE

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₁₀ClN₃O₂

[ Molecular Weight ]:
191.61500

[ Exact Mass ]:
191.04600

[ PSA ]:
92.00000

[ LogP ]:
0.86640

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

pH-sensitive cationic polymer gene delivery vehicle: N-Ac-poly(L-histidine)-graft-poly(L-lysine) comb shaped polymer.

Bioconjug. Chem. 11 , 637-645, (2000)

Advancing biotechnology spurs the development of new pharmaceutically engineered gene delivery vehicles. Poly(L-histidine) ¿PLH¿ has been shown to induce membrane fusion at endosomal pH values, wherea...

Dispersion of multi-wall carbon nanotubes in polyhistidine: Characterization and analytical applications

Anal. Chim. Acta 710 , 58-64, (2012)

Graphical abstract

Carboxymethyl poly(L-histidine) as a new pH-sensitive polypeptide to enhance polyplex gene delivery. Asayama S, Sudo M, et al.

Mol. Pharmacol. 5 , 898-901, (2008)

Poly-L-histidine
poly(1-benzylhistidine)
poly(l-lactide)
N-Fmoc-1,6-hexanediamine hydrobromide
poly-L-alanine
poly-l-methionine
1-((3-Methoxypyrazin-2-yl)methyl)azetidine-3-carboxylic acid
(S)-tert-butyl (1-((3-methoxypyrazin-2-yl)methyl)pyrrolidin-3-yl)carbamate
(R)-1-((3-methoxypyrazin-2-yl)methyl)pyrrolidin-3-ol
(R)-tert-butyl (1-((3-methoxypyrazin-2-yl)methyl)pyrrolidin-3-yl)carbamate
Tert-butyl (1-((3-methoxypyrazin-2-yl)methyl)pyrrolidin-3-yl)carbamate
1-((3-Methoxypyrazin-2-yl)methyl)piperidine-4-carboxylic acid
Tert-butyl (1-((3-methoxypyrazin-2-yl)methyl)piperidin-4-yl)carbamate
Tert-butyl ((1-((3-methoxypyrazin-2-yl)methyl)piperidin-4-yl)methyl)carbamate
1,4-Dichloro-2-propoxybenzene
1,4-Dichloro-2-(2-methylpropoxy)benzene

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