poly-l-histidine

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Names

[ CAS No. ]:
61857-39-4

[ Name ]:
poly-l-histidine

[Synonym ]:
DL-Histidin, Dihydrochlorid
POLY-L-HISTIDINE

Chemical & Physical Properties

[ Molecular Formula ]:
C6H10ClN3O2

[ Molecular Weight ]:
191.61500

[ Exact Mass ]:
191.04600

[ PSA ]:
92.00000

[ LogP ]:
0.86640

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

pH-sensitive cationic polymer gene delivery vehicle: N-Ac-poly(L-histidine)-graft-poly(L-lysine) comb shaped polymer.

Bioconjug. Chem. 11 , 637-645, (2000)

Advancing biotechnology spurs the development of new pharmaceutically engineered gene delivery vehicles. Poly(L-histidine) ¿PLH¿ has been shown to induce membrane fusion at endosomal pH values, wherea...

Dispersion of multi-wall carbon nanotubes in polyhistidine: Characterization and analytical applications

Anal. Chim. Acta 710 , 58-64, (2012)

Graphical abstract

Carboxymethyl poly(L-histidine) as a new pH-sensitive polypeptide to enhance polyplex gene delivery. Asayama S, Sudo M, et al.

Mol. Pharmacol. 5 , 898-901, (2008)


More Articles


Related Compounds

  • Poly-L-histidine
  • poly(1-benzylhistidine)
  • poly(l-lactide)
  • N-Fmoc-1,6-hexanediamine hydrobromide
  • poly-L-alanine
  • poly-l-methionine
  • 4-(4-amino-1-methyl-1H-pyrazol-5-yl)-2-methoxyphenol
  • 3-{[4-Methyl-3-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-ol
  • 3-[2-(Dimethylamino)-3,4-difluorophenyl]-1,1,1-trifluoropropan-2-one
  • (1S)-1-(2-chloro-1,3-thiazol-5-yl)-2,2,2-trifluoroethan-1-ol
  • 3-[3-(Dimethylamino)phenyl]oxolane-2,5-dione
  • 3-(1-Amino-4-hydroxycyclohexyl)-2-bromophenol
  • 2-methoxy-2-(1-methyl-1H-1,2,3-triazol-4-yl)propan-1-amine
  • 4-(1-Amino-3,3-difluorocyclobutyl)-2,6-dimethylphenol
  • Methyl 2-hydroxy-3-(3-methylpyrazin-2-yl)propanoate
  • 1-Chloro-3-fluoro-5-(1-isocyanatoethyl)benzene
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