poly-l-histidine

poly-l-histidine Structure
poly-l-histidine structure
Common Name poly-l-histidine
CAS Number 61857-39-4 Molecular Weight 191.61500
Density N/A Boiling Point N/A
Molecular Formula C6H10ClN3O2 Melting Point N/A
MSDS Chinese USA Flash Point N/A

pH-sensitive cationic polymer gene delivery vehicle: N-Ac-poly(L-histidine)-graft-poly(L-lysine) comb shaped polymer.

Bioconjug. Chem. 11 , 637-645, (2000)

Advancing biotechnology spurs the development of new pharmaceutically engineered gene delivery vehicles. Poly(L-histidine) ¿PLH¿ has been shown to induce membrane fusion at endosomal pH values, whereas PLL has a well documented efficacy in polyplex formation....

Dispersion of multi-wall carbon nanotubes in polyhistidine: Characterization and analytical applications

Anal. Chim. Acta 710 , 58-64, (2012)

Graphical abstract

Carboxymethyl poly(L-histidine) as a new pH-sensitive polypeptide to enhance polyplex gene delivery. Asayama S, Sudo M, et al.

Mol. Pharmacol. 5 , 898-901, (2008)