3-Nitrobenzyl chloride

Names

[ CAS No. ]:
619-23-8

[ Name ]:
3-Nitrobenzyl chloride

[Synonym ]:
MFCD00007272
1-(chloromethyl)-3-nitrobenzene
EINECS 210-586-1

Chemical & Physical Properties

[ Density]:
1503

[ Boiling Point ]:
85-87 °C5 mm Hg(lit.)

[ Melting Point ]:
43-47 °C(lit.)

[ Molecular Formula ]:
C₇H₆ClNO₂

[ Molecular Weight ]:
171.58100

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
171.00900

[ PSA ]:
45.82000

[ LogP ]:
2.85680

[ Index of Refraction ]:
1.5577 (62ºC)

[ Water Solubility ]:
<0.1 g/100 mL at 22 ºC

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XS9090000

CHEMICAL NAME :: Toluene, alpha-chloro-m-nitro-

CAS REGISTRY NUMBER :: 619-23-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C7-H6-Cl-N-O2

MOLECULAR WEIGHT :: 171.59

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Bacillus subtilis

DOSE/DURATION :: 500 ug/disc

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,11,1986

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
XS9090000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2904909090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Benzodiazepine receptor binding activity of 8-substituted-9-(3-substituted-benzyl)-6-(dimethylamino)-9H-purines.

J. Med. Chem. 33(1) , 196-202, (1990)

A series of 8-substituted analogues of 9-(3-aminobenzyl)-6-(dimethylamino)-9H-purine (8) were synthesized and tested for their ability to bind to the benzodiazepine receptor (BZR) in rat brain tissue....

Solvent effects on the reduction mechanism of 3-chloroanthracene, 3-nitrobenzyl chloride and 3-chloroacetophenone. Jensen H and Daasbjerg K

Acta Chir. Scand. Suppl. 58 , 1151-64, (1998)