6-Chlorobenzo[D]Isoxazol-3-Ol

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Names

[ CAS No. ]:
61977-29-5

[ Name ]:
6-Chlorobenzo[D]Isoxazol-3-Ol

[Synonym ]:
6-Chloro-1,2-benzoxazol-3(2H)-one
1,2-Benzisoxazol-3(2H)-one, 6-chloro-
6-chloro-1,2-benzoxazol-3-one
6-Chlorobenzo[D]Isoxazol-3-Ol

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
336.7±22.0 °C at 760 mmHg

[ Melting Point ]:
218-220ºC

[ Molecular Formula ]:
C7H4ClNO2

[ Molecular Weight ]:
169.565

[ Flash Point ]:
157.4±22.3 °C

[ Exact Mass ]:
168.993057

[ PSA ]:
46.26000

[ LogP ]:
1.49

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.674

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (5,6-DIMETHYL-4-OXO-3,4-DIHYDRO-THIENO[2,3-D]PYRIMIDIN-2-YL)-ACETICACIDMETHYLESTER
  • N,N-Carbonyldiimidazole
  • Benzoic acid,4-chloro-2-hydroxy-, methyl ester
  • 4-Chlorosalicylic acid

DownStream

  • 3,6-Dichlorobenzo[d]isoxazole

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Salmonella evades D-amino acid oxidase to promote infection in neutrophils.

MBio 5(6) , e01886, (2014)

Neutrophils engulf and kill bacteria using oxidative and nonoxidative mechanisms. Despite robust antimicrobial activity, neutrophils are impaired in directing Salmonella clearance and harbor viable in...

Contributions of spinal D-amino acid oxidase to chronic morphine-induced hyperalgesia.

J. Pharm. Biomed. Anal. 116 , 131-8, (2015)

Spinal D-amino acid oxidase (DAAO) is an FAD-dependent peroxisomal flavoenzyme which mediates the conversion of neutral and polar D-amino acids (including D-serine) to the corresponding α-keto acids, ...


More Articles

Related Compounds

  • (6-CHLOROBENZO[D]ISOXAZOL-3-YL)METHANAMINE
  • 5-CHLOROBENZO[D]ISOXAZOL-3-OL
  • 6-Chloro-1,2-benzoxazol-3-amine
  • 7-Chlorobenzo[d]isoxazol-3(2H)-one
  • 5-CHLOROBENZO[D]ISOXAZOL-3-YLAMINE
  • 4-Methylbenzo[d]isoxazol-3-ol
  • Tert-butyl 3-(4-aminothian-4-yl)-3-hydroxypiperidine-1-carboxylate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 6-Azaspiro[3.5]nonane-8-carboxylic acid
  • 2-Chloro-4-(oxetan-3-YL)pyrimidine
  • 1-(4-Ethylphenyl)-2-fluoroethan-1-ol
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • (4-Methyl-1,3-thiazol-2-yl)(1-methylcyclopropyl)methanol
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol