methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate

Suppliers

Names

[ CAS No. ]:
62978-52-3

[ Name ]:
methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate

[Synonym ]:
melphalan methyl ester hydrochloride salt
melphalan methylester hydrochloride

Chemical & Physical Properties

[ Density]:
1.244g/cm3

[ Boiling Point ]:
437.6ºC at 760 mmHg

[ Molecular Formula ]:
C14H20Cl2N2O2

[ Molecular Weight ]:
319.22700

[ Flash Point ]:
218.5ºC

[ Exact Mass ]:
318.09000

[ PSA ]:
55.56000

[ LogP ]:
2.71370

[ Index of Refraction ]:
1.565

Synthetic Route

Precursor & DownStream

Precursor

  • N-Boc-4-[bis(2-hydroxyethyl)amino]-L-phenylalanine Methyl Ester
  • Methanol
  • melphalan
  • 2,2-Dimethoxypropane

DownStream

  • melphalan