methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate

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Names

[ CAS No. ]:
62978-52-3

[ Name ]:
methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate

[Synonym ]:
melphalan methyl ester hydrochloride salt
melphalan methylester hydrochloride

Chemical & Physical Properties

[ Density]:
1.244g/cm3

[ Boiling Point ]:
437.6ºC at 760 mmHg

[ Molecular Formula ]:
C14H20Cl2N2O2

[ Molecular Weight ]:
319.22700

[ Flash Point ]:
218.5ºC

[ Exact Mass ]:
318.09000

[ PSA ]:
55.56000

[ LogP ]:
2.71370

[ Index of Refraction ]:
1.565

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-Boc-4-[bis(2-hydroxyethyl)amino]-L-phenylalanine Methyl Ester
  • Methanol
  • melphalan
  • 2,2-Dimethoxypropane

DownStream

  • melphalan

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine