3-(4-BROMOBENZOYL)PROPIONIC ACID

Names

[ CAS No. ]:
6340-79-0

[ Name ]:
3-(4-BROMOBENZOYL)PROPIONIC ACID

[Synonym ]:
EINECS 228-732-8
MFCD00016563
4-(4-bromophenyl)-4-oxobutanoic acid

Chemical & Physical Properties

[ Density]:
1.56 g/cm3

[ Boiling Point ]:
428ºC at 760 mmHg

[ Melting Point ]:
148-152 °C(lit.)

[ Molecular Formula ]:
C₁₀H₉BrO₃

[ Molecular Weight ]:
257.08100

[ Flash Point ]:
212.6ºC

[ Exact Mass ]:
255.97400

[ PSA ]:
54.37000

[ LogP ]:
2.49660

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Succinic anhydride
Bromobenzene
5-(4-Bromophenyl)-2-furaldehyde
2,2-dimethyl-4,6-dioxo-5-(p-bromophenacyl)-1,3-dioxane
4-(4-BROMOPHENYL)-4-OXOBUTYRONITRILE
Methyl 4-(4-bromophenyl)-4-oxobutanoate
2-Propen-1-one,1-(4-bromophenyl)-3-phenyl-
[2-bromo-3-(4-bromo-phenyl)-3-oxo-1-phenyl-propyl]-malonic acid dimethyl ester
4-bromo-3-(4-bromo-benzoyl)-4-phenyl-butyric acid methyl ester
[1-(α-bromo-benzyl)-2-(4-bromo-phenyl)-2-oxo-ethyl]-malonic acid

DownStream

7-Bromo-1,2,3,4-tetrahydronaphthalene-1-spiro-2'-(1',3'-dioxacyclopentane)
Ethyl 4-(4-bromophenyl)butanoate
4-(4-bromophenyl)butanoic acid
4-Phenylbutyric acid
7-Bromo-1-tetralone
6-(4-BROMOPHENYL)-4 5-DIHYDRO-2H-PYRIDA&
fenbufen
4-(4-BROMO-PHENYL)-4-OXO-BUTYRIC ACID ETHYL ESTER
4-Bromobenzoic acid
Acrylic acid

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

An alternative route to syntheses of aryl keto acids in a chloroaluminate ionic liquid. Mohile SS, et al.

J. Chem. Res. (M) 10 , 650-651, (2003)

2-phenylmercapto-3-(4-bromobenzoyl)propionic acid
2-acetylthiomethyl-3-(4-bromobenzoyl)propionic acid
4-(4-BROMO-PHENYL)-4-OXO-BUTYRIC ACID ETHYL ESTER
Propionic acid, 2-(m-(p-bromobenzoyl)phenoxy)-
3-(4-BROMOBENZOYL)ACRYLIC ACID
3-(4-Benzyloxyphenyl)propionic acid