2-Methoxy-5-nitrophenol

Suppliers

Names

[ CAS No. ]:
636-93-1

[ Name ]:
2-Methoxy-5-nitrophenol

[Synonym ]:
5-nitro-2-methoxyphenol
5-nitroguaiacol
Phenol,2-methoxy-5-nitro
2-Methoxy-5-nitro-phenol
MFCD00015561
2-Methoxy-5-nitrophenol
3-HYDROXY-4-METHOXYNITROBENZENE
2-Methoxy-5-nitrophe
2-Methoxy-5-nitrobenzolol
Phenol, 2-methoxy-5-nitro-
EINECS 211-269-0
2-Hydroxy-4-nitroanisole

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
291.0±0.0 °C at 760 mmHg

[ Melting Point ]:
103-107 °C(lit.)

[ Molecular Formula ]:
C7H7NO4

[ Molecular Weight ]:
169.135

[ Flash Point ]:
147.1±23.7 °C

[ Exact Mass ]:
169.037506

[ PSA ]:
75.28000

[ LogP ]:
1.80

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.583

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn,Xi

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ HS Code ]:
29095090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3,4-Methylenedioxynitrobenzene
  • 3,4-Dimethoxynitrobenzene
  • Hexylamine
  • 4-nitrocatechol
  • Dimethyl sulfate
  • Guaiacol
  • Sodium Methylate
  • Dimethylamine
  • 2-Fluoro-4-nitroanisole
  • Piperidine

DownStream

  • 3-Hydroxy-4-methoxybenzonitrile
  • 5-chloro-2-methoxyphenol
  • 2-(3-Chloropropoxy)-1-methoxy-4-nitrobenzene
  • 3,4-Dimethoxynitrobenzene
  • 4-Iodo-1,2-dimethoxybenzene
  • 2-cyclopentyloxy-1-methoxy-4-nitrobenzene
  • 3-cyclopentyloxy-4-methoxyaniline
  • N-(3-hydroxy-4-methoxyphenyl)acetamide
  • 5-Aminoguaiacol
  • 5-iodo-2-methoxyphenol

Customs

[ HS Code ]: 2909500000

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation.

Drug Metab. Dispos. 43(1) , 126-39, (2014)

Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investig...

Temperature-dependent regioselectivity of nucleophilic aromatic photosubstitution. Evidence that activation energy controls reactivity.

J. Org. Chem. 78(10) , 4834-9, (2013)

Irradiation (λ > 330 nm) of 2-chloro-4-nitroanisole (1) at 25 °C in aqueous NaOH forms three substitution photoproducts: 2-methoxy-5-nitrophenol (2), 2-chloro-4-nitrophenol (3), and 3-chloro-4-methoxy...


More Articles

Related Compounds

  • 2-METHOXY-5-NITROPHENOL ACETATE
  • Sodium 2-methoxy-5-nitrophenolate
  • 2-METHOXY-5-NITROPHENOL,SODIUMSALT
  • 4-(1-aminoethyl)-2-methoxy-5-nitrophenol
  • 4-(1-hydroxyethyl)-2-methoxy-5-nitrophenol
  • 2-methoxy-4-(methylamino)-5-nitrophenol
  • Ethyl 2-(2-ethoxy-4-fluorophenyl)-2,2-difluoroacetate
  • 2,2-Difluoro-2-(2-fluoro-4-(trifluoromethoxy)phenyl)acetic acid
  • Ethyl 2,2-difluoro-2-(3-(2-methoxyethoxy)phenyl)acetate
  • 4-(2-(4-(4-methoxyphenyl)piperazin-1-yl)-2-oxoethoxy)-2H-chromen-2-one
  • 2-Chloro-4-iodoquinazoline
  • Methyl 2-(5-(hydroxymethyl)pyrimidin-2-yl)acetate
  • Methyl 5-bromo-4-ethyl-2-hydroxybenzoate
  • 8-(Ethoxycarbonyl)-1,4-dioxaspiro[4.5]decane-8-carboxylic acid
  • tert-butyl N-[1-(4-bromophenyl)-2-oxopyrrolidin-3-yl]carbamate
  • Tert-butyl 5-bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-yl(methyl)carbamate
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