2-Methoxy-5-nitrophenol
2-Methoxy-5-nitrophenol structure
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Common Name | 2-Methoxy-5-nitrophenol | ||
|---|---|---|---|---|
| CAS Number | 636-93-1 | Molecular Weight | 169.135 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 291.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C7H7NO4 | Melting Point | 103-107 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 147.1±23.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation.
Drug Metab. Dispos. 43(1) , 126-39, (2014) Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investigated phase II biotransformation of 11 test substrates in fr... |
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Temperature-dependent regioselectivity of nucleophilic aromatic photosubstitution. Evidence that activation energy controls reactivity.
J. Org. Chem. 78(10) , 4834-9, (2013) Irradiation (λ > 330 nm) of 2-chloro-4-nitroanisole (1) at 25 °C in aqueous NaOH forms three substitution photoproducts: 2-methoxy-5-nitrophenol (2), 2-chloro-4-nitrophenol (3), and 3-chloro-4-methoxyphenol (4), in chemical yields of 69.2%, 14.3%, and 16.5%. ... |
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