N6-Cbz-L-Lysine benzyl ester hydrochloride

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Names

[ CAS No. ]:
6366-70-7

[ Name ]:
N6-Cbz-L-Lysine benzyl ester hydrochloride

[Synonym ]:
L-Lysine, N-[(phenylmethoxy)carbonyl]-, phenylmethyl ester, hydrochloride (1:1)
MFCD00038981
EINECS 228-859-9
Benzyl N-[(benzyloxy)carbonyl]-L-lysinate hydrochloride (1:1)
N6-Carbobenzyloxy-L-lysine Benzyl Ester Hydrochloride
H-Lys(Z)-OBzl·HCl

Chemical & Physical Properties

[ Density]:
1.163g/cm3

[ Boiling Point ]:
511.7ºC at 760 mmHg

[ Melting Point ]:
138-140ºC

[ Molecular Formula ]:
C21H27ClN2O4

[ Molecular Weight ]:
406.903

[ Flash Point ]:
263.2ºC

[ Exact Mass ]:
406.165924

[ PSA ]:
90.65000

[ LogP ]:
5.04700

[ Index of Refraction ]:
1.562

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OL5685000
CHEMICAL NAME :
Lysine, N(sup 6)-(phenylacetoxy)-, benzyl ester, monohydrochloride, L-
CAS REGISTRY NUMBER :
6366-70-7
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H26-N2-O4.Cl-H
MOLECULAR WEIGHT :
406.95
WISWESSER LINE NOTATION :
R1VOM4YZVO1R &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01629

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
OL5685000

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Boc-Lys(Z)-OBzl
  • N6-Cbz-L-Lysine
  • N-Boc-N'-Cbz-L-lysine
  • Benzyl alcohol
  • Benzyl bromide

DownStream

  • N6-Cbz-L-Lysine
  • benzyl 6-phenylmethoxycarbonylamino-2-[[2-(tert-butoxycarbonylamino)acetyl]amino]hexanoate

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • H-Lys(Z)-OMe.HCl
  • H-Lys(Boc)-Obzl.HCl
  • N6-Cbz-L-Lysine
  • N6-[(Methylamino)carbonyl]-N2-[(phenylmethoxy)carbonyl]-L-lysine benzyl ester
  • N'-Cbz-L-lysine tert-butyl ester hydrochloride
  • N-Benzyloxycarbonyl-L-lysine benzyl ester p-toluenesulfonate