N6-Cbz-L-Lysine benzyl ester hydrochloride

Modify Date: 2024-01-02 16:09:15

N6-Cbz-L-Lysine benzyl ester hydrochloride Structure
N6-Cbz-L-Lysine benzyl ester hydrochloride structure
Common Name N6-Cbz-L-Lysine benzyl ester hydrochloride
CAS Number 6366-70-7 Molecular Weight 406.903
Density 1.163g/cm3 Boiling Point 511.7ºC at 760 mmHg
Molecular Formula C21H27ClN2O4 Melting Point 138-140ºC
MSDS USA Flash Point 263.2ºC

 Use of N6-Cbz-L-Lysine benzyl ester hydrochloride


N6-Carbobenzoxy-L-lysine benzyl ester hydrochloride is a lysine derivative[1].

 Names

Name N6-Cbz-L-lysine Benzyl Ester Hydrochloride
Synonym More Synonyms

  Biological Activity

Description N6-Carbobenzoxy-L-lysine benzyl ester hydrochloride is a lysine derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.163g/cm3
Boiling Point 511.7ºC at 760 mmHg
Melting Point 138-140ºC
Molecular Formula C21H27ClN2O4
Molecular Weight 406.903
Flash Point 263.2ºC
Exact Mass 406.165924
PSA 90.65000
LogP 5.04700
Index of Refraction 1.562
Storage condition Store at RT.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OL5685000
CHEMICAL NAME :
Lysine, N(sup 6)-(phenylacetoxy)-, benzyl ester, monohydrochloride, L-
CAS REGISTRY NUMBER :
6366-70-7
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H26-N2-O4.Cl-H
MOLECULAR WEIGHT :
406.95
WISWESSER LINE NOTATION :
R1VOM4YZVO1R &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01629

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS OL5685000
HS Code 2924299090

 Synthetic Route

~93%

N6-Cbz-L-Lysine benzyl ester hydrochloride Structure

N6-Cbz-L-Lysine...

CAS#:6366-70-7

Literature: Kulikov, S. V.; Leonova, E. B.; Kalinina, N. M.; Samartsev, M. A.; Bubnova, L. N.; et al. Russian Journal of Bioorganic Chemistry, 1995 , vol. 21, # 6 p. 362 - 369 Bioorganicheskaya Khimiya, 1995 , vol. 21, # 6 p. 421 - 429

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N6-Cbz-L-Lysine benzyl ester hydrochloride Structure

N6-Cbz-L-Lysine...

CAS#:6366-70-7

Literature: US1312 H1, ;

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N6-Cbz-L-Lysine benzyl ester hydrochloride Structure

N6-Cbz-L-Lysine...

CAS#:6366-70-7

Literature: Journal of Medicinal Chemistry, , vol. 48, # 13 p. 4285 - 4292

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N6-Cbz-L-Lysine benzyl ester hydrochloride Structure

N6-Cbz-L-Lysine...

CAS#:6366-70-7

Literature: Bioorganic and Medicinal Chemistry, , vol. 18, # 17 p. 6220 - 6229

~%

N6-Cbz-L-Lysine benzyl ester hydrochloride Structure

N6-Cbz-L-Lysine...

CAS#:6366-70-7

Literature: Journal of Medicinal Chemistry, , vol. 48, # 13 p. 4285 - 4292

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

L-Lysine, N-[(phenylmethoxy)carbonyl]-, phenylmethyl ester, hydrochloride (1:1)
MFCD00038981
EINECS 228-859-9
Benzyl N-[(benzyloxy)carbonyl]-L-lysinate hydrochloride (1:1)
N6-Carbobenzyloxy-L-lysine Benzyl Ester Hydrochloride
H-Lys(Z)-OBzl·HCl
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