PPIase-Parvulin Inhibitor
Suppliers
Names
[ CAS No. ]:
64005-90-9
[ Name ]:
PPIase-Parvulin Inhibitor
[Synonym ]:
IN1141
diethyl 1,3,6,8-tetrahydro-1,3,6,8-tetraoxobenzo[lmn][3,8]phenanthroline-2,7-diacetate
phenanthroline-(2H,7H)-diacetate
(1,3,6,8-Tetraoxo-1,3,6,8-tetrahydro-benzo[lmn][3,8]phenanthrolin-2,7-diyl)-di-essigsaeure-diaethylester
(1,3,6,8-tetraoxo-1,3,6,8-tetrahydro-benzo[lmn][3,8]phenanthroline-2,7-diyl)-di-acetic acid diethyl ester
phenanthroline-2,7-diacetate
HIC 016C
(1,3,6,8-tetraoxo-1,3,6,8-tetrahydro-benzo[lmn][3,8]phenanthroline-2,7-diyl)-bis-acetic acid diethyl ester
Chemical & Physical Properties
[ Density]:
1.471g/cm3
[ Boiling Point ]:
636.5ºC at 760 mmHg
[ Molecular Formula ]:
C22H18N2O8
[ Molecular Weight ]:
438.38700
[ Flash Point ]:
338.7ºC
[ Exact Mass ]:
438.10600
[ PSA ]:
130.74000
[ LogP ]:
0.19180
[ Index of Refraction ]:
1.641
Safety Information
[ Symbol ]:
GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H400
[ Precautionary Statements ]:
P273
[ RIDADR ]:
UN 3077 9 / PGIII
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
EJNMMI Res. 5 , 20, (2015)
Over the last decade, an increasing number of studies have been published on the use of amyloid-β (Aβ) PET imaging with different (18)F-radiopharmaceuticals for clinical characterization of Alzheimer'...
Curr. Alzheimer Res. 12 , 563-71, (2015)
Alzheimer's disease (AD) is the most common neurodegenerative disorder pathologically characterized by amyloid-beta (Aβ) plaques and neurofibrillary tangles. The aggregation of Aβ precedes tau patholo...
J. Alzheimers Dis. 46 , 63-73, (2015)
Even low levels of depressive symptoms are associated with an increased risk of cognitive decline in older adults without overt cognitive impairment (CN). Our objective was to examine whether very low...