Paroxetine maleate
Suppliers
Names
[ CAS No. ]:
64006-44-6
[ Name ]:
Paroxetine maleate
[Synonym ]:
fg7051maleate
gf74
MFCD01742665
Paroxetine maleate
Chemical & Physical Properties
[ Density]:
1.213 g/cm3
[ Boiling Point ]:
451.7ºC at 760 mmHg
[ Melting Point ]:
136-138ºC
[ Molecular Formula ]:
C23H24FNO7
[ Molecular Weight ]:
445.44
[ Flash Point ]:
227ºC
[ Exact Mass ]:
445.15400
[ PSA ]:
114.32000
[ LogP ]:
3.36710
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM4569300
- CHEMICAL NAME :
- Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl )-, trans-(-)-, (Z)-2- butenedioate
- CAS REGISTRY NUMBER :
- 64006-44-6
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C19-H20-F-N-O3.xC4-H4-O4
- MOLECULAR WEIGHT :
- 1141.96
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 6700 ug/kg
- TOXIC EFFECTS :
- Behavioral - excitement
- REFERENCE :
- AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- Volume(issue)/page/year: 11,682,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4007196
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 845 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,1114,1989
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
UN 3249
[ WGK Germany ]:
3
[ RTECS ]:
TM4569300
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
Articles
J. Clin. Psychopharmacol. 33(1) , 3-10, (2013)
The potential for iloperidone, a D2/5-HT2A antipsychotic, to affect the heart rate-corrected QT interval (QTc) was assessed in the absence and presence of metabolic inhibitors in a randomized, open-la...
Semin. Ophthalmol. 28(4) , 244-6, (2013)
To present a unique case of a 33-year-old woman using paroxetine who presented with acute unilateral visual loss due to chronic angle-closure glaucoma.Case report.A 33-year-old women who had been unde...
Med. Lett. Drugs Ther. 55(1428) , 85-6, (2013)