N-Boc-L-Norleucine

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Names

[ CAS No. ]:
6404-28-0

[ Name ]:
N-Boc-L-Norleucine

[Synonym ]:
MFCD00037270
N-(tert-Butoxycarbonyl)-L-norleucine
L-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-norleucine
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
Boc-Nle-OH
N-(tert-Butoxycarbonyl)norleucine

Chemical & Physical Properties

[ Density]:
1.063±0.06 g/cm3

[ Boiling Point ]:
362.1±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H21NO4

[ Molecular Weight ]:
231.289

[ Flash Point ]:
172.8±23.2 °C

[ Exact Mass ]:
231.147064

[ PSA ]:
75.63000

[ LogP ]:
2.69

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.463

[ Storage condition ]:
-15°C

[ Water Solubility ]:
Slightly soluble (1.5 g/L) (25 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • L-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
  • (4S,5R)-3-tert-butoxycarbonyl-4-butyl-5-methoxy-2-oxazolidinone
  • Z-Ser-OtBu
  • Carbonazidic acid,1,1-dimethylethyl ester
  • L-Norleucine
  • Di-tert-butyl dicarbonate
  • 2-Oxazolidinone,4-butyl-5-methoxy-,(4S,5R)-(9CI)
  • Ser-OtBu

DownStream

  • [Nle11]-Substance P
  • Boc-N-Me-Nle-OH
  • Boc-L-norleucine N-hydroxysuccinimide ester
  • 1-Benzyl-3-butylpiperazine
  • (S)-1-BOC-2-BUTYLPIPERAZINE

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • N-Boc-6-azido-L-norleucine (dicyclohexylammonium) salt
  • N-Boc-L-arginine hydrochloride monohydrate
  • N-Boc-L-homoserine Methyl Ester 4-Methylbenzenesulfonate
  • N-Boc-L-felinine
  • N-Boc-L-valinol
  • N-Boc-L-Pro-L-Pro methyl ester
  • [5-(1-methoxyethyl)-1-(2-methylpropyl)-1H-1,2,3-triazol-4-yl]methanamine
  • 2-(4-(4-Methoxyphenyl)piperidin-1-yl)acetic acid hydrochloride
  • Ethyl 6-Chloro-[1,2,4]triazolo[4,3-a]pyridine-7-carboxylate
  • 4-Fluoro-3-isopropoxy-5-methylbenzaldehyde
  • Methyl 6-Chloro-[1,2,4]triazolo[4,3-a]pyridine-7-carboxylate
  • 3-(Aminomethyl)-4-iodobenzoic acid
  • 4-(2-Fluoro-3-methoxypyridin-4-yl)benzaldehyde
  • 3-[4-[(Boc-amino)methyl]phenyl]oxetan-3-ol
  • N-Boc-1-[4-(3-fluorooxetan-3-yl)phenyl]methanamine
  • 3-(2-Phenyl-2-propyl)-5-(2,3,3-trimethyl-2-butyl)cyclohexa-3,5-diene-1,2-dione
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