N-Carbobenzoxy-4-oxo-L-proline

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Names

[ CAS No. ]:
64187-47-9

[ Name ]:
N-Carbobenzoxy-4-oxo-L-proline

[Synonym ]:
N-Carbobenzyloxy-4-keto-L-proline
1-[(Benzyloxy)carbonyl]-4-oxo-L-proline
1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1-(phenylmethyl) ester, (2S)-
(2S)-4-oxo-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
N-Carbobenzoxy-4-oxo-L-proline
(S)-1-(benzyloxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
488.5±45.0 °C at 760 mmHg

[ Melting Point ]:
95℃

[ Molecular Formula ]:
C13H13NO5

[ Molecular Weight ]:
263.246

[ Flash Point ]:
249.2±28.7 °C

[ Exact Mass ]:
263.079376

[ PSA ]:
83.91000

[ LogP ]:
0.18

[ Appearance of Characters ]:
Powder | White to yellow to brown

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.597

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36-37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Z-Hyp-OH
  • L-Hydroxyproline
  • Benzyl chloroformate

DownStream

  • L-ERYTHRO-4-FLUORO-GLUTAMIC ACID
  • Spirapril hydrochloride
  • (2S,4S)-4-Benzylpyrrolidine-2-carboxylic acid
  • Spirapril
  • Z-Hyp-Ome
  • trans-4-Carboxy-L-proline
  • cis-4-hydroxy-L-proline
  • (4S)-1-[(Benzyloxy)carbonyl]-4-hydroxy-L-proline
  • Z-Hyp-OH
  • Methyl (S)-1-Cbz-4-oxo-2-pyrrolidinecarboxylate

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • N-Carbobenzoxy-4-oxo-L-proline
  • N-Boc-4-oxo-L-proline
  • N-benzoyl-4-oxo-L-proline tert-butyl ester
  • N-Boc-4-oxo-L-proline methyl ester
  • N-carbobenzoxy-L-proline phenylmethyl ester
  • (S)-di-tert-butyl 4-oxopyrrolidine-1,2-dicarboxylate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 2-Hydroxy-3-(tritylthio)propanoic acid
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide