Quinoline-3-carboxylic acid

Suppliers

Names

[ CAS No. ]:
6480-68-8

[ Name ]:
Quinoline-3-carboxylic acid

[Synonym ]:
EINECS 229-337-3
MFCD00006770
3-Quinolinecarboxylic acid
Quinoline-3-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
348.7±17.0 °C at 760 mmHg

[ Melting Point ]:
277-280 °C(lit.)

[ Molecular Formula ]:
C10H7NO2

[ Molecular Weight ]:
173.168

[ Flash Point ]:
164.7±20.9 °C

[ Exact Mass ]:
173.047684

[ PSA ]:
50.19000

[ LogP ]:
2.18

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.685

[ Storage condition ]:
Refrigerator

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25-S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933499090

Synthetic Route

Precursor & DownStream

Precursor

  • 3-Methylquinoline
  • 3-Bromoquinoline
  • carbon monoxide
  • D-Phenylglycine ethyl ester hydrochloride
  • 3-(Bromomethyl)quinoline
  • 3-CYANOQUINOLINE
  • 3-Quinolinecarboxaldehyde
  • Carbon dioxide
  • Potassium formate
  • 1-(3-Quinolinyl)ethanone

DownStream

  • Ethyl 3-quinolinecarboxylate
  • 1-Methyl-1,2,3,4-tetrahydroquinoline
  • methyl quinoline-3-carboxylate
  • 3-Quinolinylmethanol
  • 1,2,3,4-Tetrahydro-3-quinolinecarboxylic acid
  • 3-Quinolinecarboxaldehyde
  • quinoline-3-carboxamide
  • methyl 2,4-dicyclopentylquinoline-3-carboxylate
  • 3-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-, ethyl ester
  • Quinoline-3-carbonyl chloride

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Effects of norfloxacin on hepatic genes expression of P450 isoforms (CYP1A and CYP3A), GST and P-glycoprotein (P-gp) in Swordtail fish (Xiphophorus Helleri).

Ecotoxicology 24 , 1566-73, (2015)

The presence of antibiotics including norfloxacin in the aquatic environment may cause adverse effects in non-target organisms. But the toxic mechanisms of fluoroquinolone to fish species are still no...

Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties.

J. Med. Chem. 49 , 6897-907, (2006)

Starting from a yeast phenotypic screening performed on 21 compounds, we described the identification of two small molecules (9 and 18) able to significantly reduce the S. cerevisiae cell growth, thus...

Novel amino-substituted 3-quinolinecarboxylic acid antibacterial agents: synthesis and structure-activity relationships.

J. Med. Chem. 27(9) , 1103-8, (1984)

A series of novel 3-quinolinecarboxylic acid derivatives have been prepared and their antibacterial activity evaluated. These derivatives are characterized by fluorine attached to the 6-position and s...


More Articles


Related Compounds

  • quinoline-3-carboxylic acid
  • 6-BROMOQUINOLINE-3-CARBOXYLIC ACID
  • 8-Ethylquinoline-3-carboxylic acid
  • 8-methylquinoline-3-carboxylic acid
  • 8-ethyl-quinoline-3-carboxylic acid
  • 6-fluoroquinoline-3-carboxylic acid
  • 1-(4-Chlorophenyl)-3-(5-methyl-4-oxo-4,5-dihydro-1,3-thiazol-2-yl)urea
  • 3-(4-Chlorophenyl)-2-[(4,6-dimethylpyrimidin-2-yl)amino]-6-oxo-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
  • 5-Imino-4-[(4-methylphenyl)hydrazinylidene]-1-phenylpyrazolidin-3-one
  • 2-(Morpholin-4-ylmethyl)-4-oxo-3,4-dihydroquinazoline-7-carboxylic acid
  • N-[4-[[[(Z)-(2-methylindol-3-ylidene)methyl]amino]carbamoyl]phenyl]butanamide
  • (5Z)-5-(4-ethoxy-3-methoxybenzylidene)-2-[(4-methylphenyl)amino]-1,3-thiazol-4(5H)-one
  • (2E,5Z)-2-[(3,5-dichlorophenyl)imino]-5-(pyridin-3-ylmethylidene)-1,3-thiazolidin-4-one
  • (5Z)-2-[(2,4-dichlorophenyl)amino]-5-(4-fluorobenzylidene)-1,3-thiazol-4(5H)-one
  • (5Z)-2-[(3,5-dichlorophenyl)amino]-5-(4-fluorobenzylidene)-1,3-thiazol-4(5H)-one
  • (5Z)-2-[(4-chlorophenyl)amino]-5-(4-hydroxy-3-methoxybenzylidene)-1,3-thiazol-4(5H)-one
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