Quinoline-3-carboxylic acid

Quinoline-3-carboxylic acid Structure
Quinoline-3-carboxylic acid structure
Common Name Quinoline-3-carboxylic acid
CAS Number 6480-68-8 Molecular Weight 173.168
Density 1.3±0.1 g/cm3 Boiling Point 348.7±17.0 °C at 760 mmHg
Molecular Formula C10H7NO2 Melting Point 277-280 °C(lit.)
MSDS Chinese USA Flash Point 164.7±20.9 °C

Effects of norfloxacin on hepatic genes expression of P450 isoforms (CYP1A and CYP3A), GST and P-glycoprotein (P-gp) in Swordtail fish (Xiphophorus Helleri).

Ecotoxicology 24 , 1566-73, (2015)

The presence of antibiotics including norfloxacin in the aquatic environment may cause adverse effects in non-target organisms. But the toxic mechanisms of fluoroquinolone to fish species are still not completely elucidated. Thus, it is essential to investiga...

Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties.

J. Med. Chem. 49 , 6897-907, (2006)

Starting from a yeast phenotypic screening performed on 21 compounds, we described the identification of two small molecules (9 and 18) able to significantly reduce the S. cerevisiae cell growth, thus miming the effect of GCN5 deletion mutant. Tested on a GCN...

Novel amino-substituted 3-quinolinecarboxylic acid antibacterial agents: synthesis and structure-activity relationships.

J. Med. Chem. 27(9) , 1103-8, (1984)

A series of novel 3-quinolinecarboxylic acid derivatives have been prepared and their antibacterial activity evaluated. These derivatives are characterized by fluorine attached to the 6-position and substituted amino groups appended to the 1- and 7-positions....