Lisofylline

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Names

[ CAS No. ]:
6493-06-7

[ Name ]:
Lisofylline

[Synonym ]:
R-1-(5-Hydroxyhexyl)-3,7-dimethylxanthine
(R)-3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione
1-[(5R)-5-Hydroxyhexyl]-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Penthydroxifillyne
HYDROXY PENTOXIFYLLINE
Lisofylline
1-(5-Hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
1H-Purine-2,6-dione, 3,7-dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-
UNII:R99EE080JS
1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-
ProTec
1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-, (R)-
1-[(R)-5-Hydroxyhexyl]theobromine
CT 1501R

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
511.2±56.0 °C at 760 mmHg

[ Melting Point ]:
123-125ºC

[ Molecular Formula ]:
C13H20N4O3

[ Molecular Weight ]:
280.323

[ Flash Point ]:
263.0±31.8 °C

[ Exact Mass ]:
280.153534

[ PSA ]:
82.05000

[ LogP ]:
0.34

[ Appearance of Characters ]:
solid | white

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.621

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
DMSO: soluble

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • Pentoxifylline

DownStream

Articles

Calcitonin gene-related peptide inhibits human immunodeficiency type 1 transmission by Langerhans cells via an autocrine/paracrine feedback mechanism.

Acta Physiol. (Oxf.) 213(2) , 432-41, (2015)

Peripheral neurones innervating mucosal epithelia are in direct contact with resident immune cells, including Langerhans cells (LCs). Such neurones secrete the neuropeptide calcitonin gene-related pep...


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Related Compounds

  • Lisofylline
  • (S)-Lisofylline
  • (±)-Lisofylline-d6
  • (±)-Lisofylline-d6 (alkyl)
  • 5'-O-Acetyl (R)-Lisofylline
  • [5-(Hydroxymethyl)piperidinyl]methanol
  • 6-Bromo-7-fluoro-N4,8-dimethylquinoline-3,4-diamine
  • 1,1,1-Trifluoro-3,5,5-trimethylhexane-2,4-dione
  • 3,4-Dihydro-6,7-dimethoxy-3,3,4-trimethyl-1-phenylisoquinoline
  • 3-[[[4-Bromo-5-(4-morpholinyl)-2-furanyl]methylene]amino]-4-methylbenzoic acid
  • 2-[4-[[(4-Butylphenyl)imino]methyl]-2-chlorophenoxy]acetic acid
  • N-[[4-Bromo-5-(1-pyrrolidinyl)-2-furanyl]methylene]benzenemethanamine
  • N-[(1,2-Dimethyl-1H-indol-3-yl)methylene]-2-naphthalenamine
  • 3-[[2-Methoxy-4-[(phenylimino)methyl]phenoxy]methyl]benzoic acid
  • N-[[4-Bromo-5-[(4-chlorophenyl)thio]-2-furanyl]methylene]benzenemethanamine
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