Morazone

Suppliers

Names

[ CAS No. ]:
6536-18-1

[ Name ]:
Morazone

[Synonym ]:
1,5-dimethyl-4-(3-methyl-2-phenyl-morpholinomethyl)-2-phenyl-1,2-dihydro-pyrazol-3-one
1,5-Dimethyl-4-(3-methyl-2-phenyl-morpholinomethyl)-2-phenyl-1,2-dihydro-pyrazol-3-on
Morazonum [INN-Latin]
R 445
EINECS 229-447-1
Morazone
1,5-dimethyl-4-(3-methyl-2-phenyl-morpholin-4-ylmethyl)-2-phenyl-1,2-dihydro-pyrazol-3-one
Tarugan
Novartrina
Morazona [INN-Spanish]
Orsimon

Chemical & Physical Properties

[ Density]:
1.153g/cm3

[ Boiling Point ]:
503.9ºC at 760 mmHg

[ Molecular Formula ]:
C23H27N3O2

[ Molecular Weight ]:
377.47900

[ Flash Point ]:
258.5ºC

[ Exact Mass ]:
377.21000

[ PSA ]:
39.40000

[ LogP ]:
3.38430

[ Index of Refraction ]:
1.587

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ9200000
CHEMICAL NAME :
3-Pyrazolin-5-one, 2,3-dimethyl-4-(3-methyl-2-phenylmorpholino)methyl-1- phenyl-
CAS REGISTRY NUMBER :
6536-18-1
BEILSTEIN REFERENCE NO. :
0347917
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C23-H27-N3-O2
MOLECULAR WEIGHT :
377.53
WISWESSER LINE NOTATION :
T6N DOTJ B1 CR& A1- DT5NNVJ A1 BR E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 5,346,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 5,346,1965

Synthetic Route

Precursor & DownStream

Precursor

  • Formaldehyde
  • PHENMETRAZINE
  • Antipyrine

DownStream

  • 4-(hydroxymethyl)-1,5-dimethyl-2-phenylpyrazol-3-one
  • PHENMETRAZINE
  • Morazone-d3 Hydrochloride

Related Compounds

  • Morazone Hydrochloride
  • 1-Allyl-3,5-dimethyl-1H-pyrazol-4-amine
  • 5-amino-2,3-dihydro-1H-pyrrol-2-one
  • Perphenazine trihydrochloride
  • 2-Methyl-1,5-naphthalenediamine
  • 3-(2-Chloropyridine-3-sulfonamido)benzoic acid
  • N-(2-methylpropyl)-3-(1H-tetrazol-1-yl)benzamide
  • (6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)(2-methyl-1,3-benzothiazol-6-yl)methanone
  • {4-[(4-Methoxyphenyl)sulfonyl]piperazino}(2-methyl-1,3-benzothiazol-6-yl)methanone
  • [4-(2-Methoxyphenyl)piperazin-1-yl][2-(trifluoromethyl)-1,3-benzothiazol-6-yl]methanone
  • N-(furan-2-ylmethyl)-2-(trifluoromethyl)-1,3-benzothiazole-6-carboxamide
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