Altholactone

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
490.4±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₂O₄

[ Molecular Weight ]:
232.23

[ Flash Point ]:
196.1±22.2 °C

[ Exact Mass ]:
232.073563

[ PSA ]:
55.76000

[ LogP ]:
1.00

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.598

[ Storage condition ]:
?20°C

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2811 6.1 / PGIII

Stereoselective total synthesis of bioactive styryllactones (+)-goniofufurone, (+)7-epi-goniofufurone, (+)-goniopypyrone, (+)-goniotriol, (+)-altholactone, and (-)-etharvensin.

J. Org. Chem. 73(1) , 2-11, (2008)

Stereoselective total synthesis of biologically active styryllactones 7-epi-goniofufurone, goniofufurone, goniopypyrone, goniotriol, altholactone, and etharvensin was achieved in high overall yields f...

The cytotoxicity of naturally occurring styryl lactones.

Phytomedicine 13(3) , 181-6, (2006)

We extracted and isolated three natural styryl lactones from Goniothalamus griffithii Hook f. Thoms and investigated their cytotoxicity on a panel of three hepatocyte cell lines, HepG2, drug resistant...

Asymmetric synthesis of (+)-altholactone: a styryllactone isolated from various Goniothalamus species.

Chemistry 14(9) , 2842-9, (2008)

The asymmetric total synthesis of (+)-altholactone (1), a member of the styryllactone family of natural products displaying cytotoxic and antitumor activities, is described. Key steps include a RAMP-h...

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