1,10-Phenanthroline
Suppliers
Names
[ CAS No. ]:
66-71-7
[ Name ]:
1,10-Phenanthroline
[Synonym ]:
1,10-Phenanthroline
4,5-Diazaphenanthrene
4,5-Phenanthroline
ORTHOPHENANTHROLINE
EINECS 200-629-2
1,10-o-Phenanthroline
o-Phenanthroline
β-Phenanthroline
1,10-Fenanthroline
phenanthroline
MFCD00011678
1,10-Fenanthrolin
phen
10-Phenanthroline
T B666 CN NNJ
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
365.1±15.0 °C at 760 mmHg
[ Melting Point ]:
114-117 °C(lit.)
[ Molecular Formula ]:
C12H8N2
[ Molecular Weight ]:
180.205
[ Flash Point ]:
164.8±11.7 °C
[ Exact Mass ]:
180.068741
[ PSA ]:
25.78000
[ LogP ]:
1.78
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.740
[ Storage condition ]:
Refrigerator
[ Stability ]:
Stable. Hygroscopic. Store under nitrogen. Incompatible with strong acids, strong oxidizing agents.
[ Water Solubility ]:
slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SF8300000
- CHEMICAL NAME :
- 1,10-Phenanthroline
- CAS REGISTRY NUMBER :
- 66-71-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C12-H8-N2
- MOLECULAR WEIGHT :
- 180.22
- WISWESSER LINE NOTATION :
- T B666 CN NNJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Kidney, Ureter, Bladder - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 18 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 30 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Leukocyte
- DOSE/DURATION :
- 5 mg/L
- REFERENCE :
- ONCOBS Oncology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.21- 1967- Volume(issue)/page/year: 46,193,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82276 No. of Facilities: 1002 (estimated) No. of Industries: 12 No. of Occupations: 11 No. of Employees: 8324 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82276 No. of Facilities: 2265 (estimated) No. of Industries: 33 No. of Occupations: 35 No. of Employees: 40330 (estimated) No. of Female Employees: 2577 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H410
[ Precautionary Statements ]:
P273-P301 + P310-P501
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R25;R50/53
[ Safety Phrases ]:
S45-S60-S61
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
SF8437000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
29339990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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