Metyrosine

Names

[ CAS No. ]:
672-87-7

[ Name ]:
Metyrosine

[Synonym ]:
MFCD00064201
(S)-alpha-Methyltyrosine
α-METHYL-L-P-TYROSINE
alpha-methyl-L-tyrosine
EINECS 211-599-5

Chemical & Physical Properties

[ Density]:
1.283g/cm3

[ Boiling Point ]:
383.7ºC at 760 mmHg

[ Melting Point ]:
320-340°C dec.

[ Molecular Formula ]:
C₁₀H₁₃NO₃

[ Molecular Weight ]:
195.21500

[ Flash Point ]:
185.9ºC

[ Exact Mass ]:
195.09000

[ PSA ]:
83.55000

[ LogP ]:
1.43700

[ Index of Refraction ]:
1.599

[ Storage condition ]:
−20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

FDA-approved drug labeling for the study of drug-induced liver injury.

Drug Discov. Today 16 , 697-703, (2011)

Drug-induced liver injury (DILI) is a leading cause of drugs failing during clinical trials and being withdrawn from the market. Comparative analysis of drugs based on their DILI potential is an effec...

Effects of intratumoral inflammatory process on 18F-FDG uptake: pathologic and comparative study with 18F-fluoro-α-methyltyrosine PET/CT in oral squamous cell carcinoma.

J. Nucl. Med. 56(1) , 16-21, (2015)

The accurate depiction of both biologic and anatomic profiles of tumors has long been a challenge in PET imaging. An inflammation, which is innate in the carcinogenesis of oral squamous cell carcinoma...