Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one
Suppliers
Names
[ CAS No. ]:
67200-34-4
[ Name ]:
Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one
[Synonym ]:
Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one,
5-Oxoindeno<1,2-e>furazano<3,4-b>pyrazin
Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one
9H-Indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one
2-Oxa-1,3,4,10-tetraaza-cyclopenta[b]fluoren-9-one
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
437.2±55.0 °C at 760 mmHg
[ Melting Point ]:
296 °C(dec.)
[ Molecular Formula ]:
C11H4N4O2
[ Molecular Weight ]:
224.175
[ Flash Point ]:
218.2±31.5 °C
[ Exact Mass ]:
224.033432
[ PSA ]:
81.77000
[ LogP ]:
0.90
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
[ Index of Refraction ]:
1.779
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Nat. Biotechnol. 28 , 738 - 742, (2010)
The target of rapamycin (TOR) plays a central role in eukaryotic cell growth control. With prevalent hyperactivation of the mammalian TOR (mTOR) pathway in human cancers, strategies to enhance TOR pat...