2-Hydroxy-4-methoxybenzaldehyde

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Names

[ CAS No. ]:
673-22-3

[ Name ]:
2-Hydroxy-4-methoxybenzaldehyde

[Synonym ]:
o-Hydroxy-p-methoxybenzaldehyde
VHR BQ DO1
2-HO-4-MeO-C6H3CHO
2-Hydroxy-4-methoxybenzaldehyde
4-Methoxysalicylaldehyde
4-Methoxysalicyaldehyde
Salicylaldehyde, 4-methoxy-
Benzaldehyde,2-hydroxy-4-methoxy
2-Hydroxy-p-anisaldehyde
Benzaldehyde, 2-hydroxy-4-methoxy-
p-Anisaldehyde,2-hydroxy
2-hydroxy-4-methoxy benzaldehyde
4-methoxy-salicylaldehyde
Salicylaldehyde,4-methoxy
EINECS 211-604-0
4-methoxy-2-hydroxybenzaldehyde
MFCD00003327
p-Anisaldehyde, 2-hydroxy-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
271.5±20.0 °C at 760 mmHg

[ Melting Point ]:
41-43 °C(lit.)

[ Molecular Formula ]:
C8H8O3

[ Molecular Weight ]:
152.15

[ Flash Point ]:
112.1±15.3 °C

[ Exact Mass ]:
152.047348

[ PSA ]:
46.53000

[ LogP ]:
1.79

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.588

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BZ2810000
CHEMICAL NAME :
p-Anisaldehyde, 2-hydroxy-
CAS REGISTRY NUMBER :
673-22-3
BEILSTEIN REFERENCE NO. :
1072443
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H8-O3
MOLECULAR WEIGHT :
152.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
500 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
BZ2810000

[ HS Code ]:
29124900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Dimethyl sulfate
  • b-Resorcylaldehyde
  • 2,4-dimethoxybenzaldehyde
  • Formaldehyde
  • m-Methoxyphenol
  • methyl iodide
  • 5-Methoxy-2-formylphenylboronic acid
  • ethyl (E)-3-(2-formyl-5-methoxyphenoxy)acrylate
  • p-Toluidine
  • Methyl bromide

DownStream

  • 2-Oxo-2H-chromen-7-yl Trifluoromethanesulfonate
  • Benzaldehyde, 4-Methoxy-2-(1-Methylethoxy)-
  • (3S)-3,4-Dihydro-7-methoxy-3-(4-methoxyphenyl)-2H-1-benzopyran
  • 6-METHOXYBENZOFURAN-2-CARBOXYLIC ACID
  • 2-Hydroxy-4-methoxybenzonitrile
  • 6-METHOXYBENZOFURAN
  • 2,4-Dimethoxybenzonitrile
  • Osthole
  • 7-Methoxychroman-4-one
  • (6-Methoxy-1-benzofuran-2-yl)methanol

Customs

[ HS Code ]: 2912499000

[ Summary ]:
2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

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Related Compounds

  • 3-allyl-2-hydroxy-4-methoxybenzaldehyde
  • 5-ethyl-2-hydroxy-4-methoxybenzaldehyde
  • 3-bromo-2-hydroxy-4-methoxybenzaldehyde
  • 5-Bromo-2-hydroxy-4-methoxybenzaldehyde
  • 3-chloro-2-hydroxy-4-methoxybenzaldehyde
  • 5-Chloro-2-hydroxy-4-methoxybenzaldehyde
  • 4-((2-Chlorobenzyl)thio)-2-(o-tolyl)pyrazolo[1,5-a]pyrazine
  • 4-[(4-Chlorobenzyl)thio]-2-(2-methylphenyl)pyrazolo[1,5-a]pyrazine
  • 5-Methyl-2-(p-tolyl)-4-(((2-(o-tolyl)pyrazolo[1,5-a]pyrazin-4-yl)thio)methyl)oxazole
  • 4-({[2-(4-Ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}thio)-2-(2-methylphenyl)pyrazolo[1,5-a]pyrazine
  • 4-({[2-(3-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl}thio)-2-(2-methylphenyl)pyrazolo[1,5-a]pyrazine
  • 4-({[2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl}thio)-2-(2-methylphenyl)pyrazolo[1,5-a]pyrazine
  • 4-({[2-(4-Isopropoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}thio)-2-(2-methylphenyl)pyrazolo[1,5-a]pyrazine
  • 2-(2-Methylphenyl)-4-{[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]sulfanyl}pyrazolo[1,5-a]pyrazine
  • 4-({[2-(4-Methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}thio)-2-(2-methylphenyl)pyrazolo[1,5-a]pyrazine
  • 4-({[5-Methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methyl}thio)-2-(2-methylphenyl)pyrazolo[1,5-a]pyrazine
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