2-Hydroxy-4-methoxybenzaldehyde
2-Hydroxy-4-methoxybenzaldehyde structure
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Common Name | 2-Hydroxy-4-methoxybenzaldehyde | ||
|---|---|---|---|---|
| CAS Number | 673-22-3 | Molecular Weight | 152.15 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 271.5±20.0 °C at 760 mmHg | |
| Molecular Formula | C8H8O3 | Melting Point | 41-43 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 112.1±15.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 2-Hydroxy-4-methoxybenzaldehyde2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7[1]. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor from three East African medicinal plants, Mondia whitei, Rhus vulgaris Meikle, and Sclerocarya caffra Sond[2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-Hydroxy-4-methoxybenzaldehyde |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7[1]. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor from three East African medicinal plants, Mondia whitei, Rhus vulgaris Meikle, and Sclerocarya caffra Sond[2]. |
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| Related Catalog | |
| Target |
Tyrosinase[2]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 271.5±20.0 °C at 760 mmHg |
| Melting Point | 41-43 °C(lit.) |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 |
| Flash Point | 112.1±15.3 °C |
| Exact Mass | 152.047348 |
| PSA | 46.53000 |
| LogP | 1.79 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.588 |
| InChIKey | WZUODJNEIXSNEU-UHFFFAOYSA-N |
| SMILES | COc1ccc(C=O)c(O)c1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | BZ2810000 |
| HS Code | 29124900 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 10 | |
CAS#:77-78-1
CAS#:95-01-2
CAS#:613-45-6
CAS#:50-00-0
CAS#:150-19-6
CAS#:74-88-4
CAS#:40138-18-9
CAS#:954374-77-7
CAS#:106-49-0
CAS#:74-83-9
CAS#:108530-10-5
CAS#:107811-48-3
CAS#:3722-56-3
CAS#:50551-61-6
CAS#:39835-11-5
CAS#:50551-63-8
CAS#:4107-65-7
CAS#:484-12-8
CAS#:42327-52-6
CAS#:208842-22-2This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2912499000 |
|---|---|
| Summary | 2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.
Bioorg. Med. Chem. 15 , 2006-15, (2007) Phenoloxidase (PO), also known as tyrosinase, is a key enzyme in insect development, responsible for catalyzing the hydroxylation of tyrosine into o-diphenols and the oxidation of o-diphenols into o-q... |
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Flavoring extracts of Hemidesmus indicus roots and Vanilla planifolia pods exhibit in vitro acetylcholinesterase inhibitory activities.
Plant Foods Hum. Nutr. 68(3) , 247-53, (2013) Acetylcholinesterase inhibitors (AChEIs) are important for treatment of Alzheimer's disease and other neurological disorders. Search for potent and safe AChEIs from plant sources still continues. In t... |
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Inhibition of Cancer Cell Proliferation and Antiradical Effects of Decoction, Hydroalcoholic Extract, and Principal Constituents of Hemidesmus indicus R. Br.
Phytother Res. 29 , 857-63, (2015) Indian Sarsaparilla (Hemidesmus indicus R. Br.) is widely used in Indian traditional medicine. In the present work, we explored the effects of decoction, traditional Ayurvedic preparation, and hydroal... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| o-Hydroxy-p-methoxybenzaldehyde |
| VHR BQ DO1 |
| 2-HO-4-MeO-C6H3CHO |
| 2-Hydroxy-4-methoxybenzaldehyde |
| 4-Methoxysalicylaldehyde |
| 4-Methoxysalicyaldehyde |
| Benzaldehyde,2-hydroxy-4-methoxy |
| 2-Hydroxy-p-anisaldehyde |
| p-Anisaldehyde,2-hydroxy |
| 2-hydroxy-4-methoxy benzaldehyde |
| 4-methoxy-salicylaldehyde |
| Salicylaldehyde,4-methoxy |
| EINECS 211-604-0 |
| 4-methoxy-2-hydroxybenzaldehyde |
| MFCD00003327 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of 2-Hydroxy-4-methoxybenzaldehyde? |
| A: Molecular weight of 2-Hydroxy-4-methoxybenzaldehyde is 152.15. |
| Q: What are the upstream materials of 2-Hydroxy-4-methoxybenzaldehyde? |
| A: Related upstream materials(CAS) of 2-Hydroxy-4-methoxybenzaldehyde: 77-78-1;95-01-2;613-45-6;50-00-0;150-19-6;74-88-4;40138-18-9;954374-77-7;106-49-0;74-83-9. |
| Q: What is the polar surface area (PSA) of 2-Hydroxy-4-methoxybenzaldehyde? |
| A: Polar surface area (PSA) of 2-Hydroxy-4-methoxybenzaldehyde is 46.53000. |
| Q: What is the English name of 2-Hydroxy-4-methoxybenzaldehyde? |
| A: The English name of 2-Hydroxy-4-methoxybenzaldehyde is 2-Hydroxy-4-methoxybenzaldehyde. |
| Q: What is the safety information for 2-Hydroxy-4-methoxybenzaldehyde? |
| A: Safety information for 2-Hydroxy-4-methoxybenzaldehyde: S26-S36-S24/25. |
| Q: What is the SMILES notation of 2-Hydroxy-4-methoxybenzaldehyde? |
| A: SMILES notation of 2-Hydroxy-4-methoxybenzaldehyde is COc1ccc(C=O)c(O)c1. |
| Q: What English synonyms does 2-Hydroxy-4-methoxybenzaldehyde have? |
| A: English synonyms of 2-Hydroxy-4-methoxybenzaldehyde: o-Hydroxy-p-methoxybenzaldehyde, VHR BQ DO1, 2-HO-4-MeO-C6H3CHO, 2-Hydroxy-4-methoxybenzaldehyde, 4-Methoxysalicylaldehyde, 4-Methoxysalicyaldehyde, Benzaldehyde,2-hydroxy-4-methoxy, 2-Hydroxy-p-anisaldehyde, p-Anisaldehyde,2-hydroxy, 2-hydroxy-4-methoxy benzaldehyde, 4-methoxy-salicylaldehyde, Salicylaldehyde,4-methoxy, EINECS 211-604-0, 4-methoxy-2-hydroxybenzaldehyde, MFCD00003327. |
| Q: What is the melting point of 2-Hydroxy-4-methoxybenzaldehyde? |
| A: Melting point of 2-Hydroxy-4-methoxybenzaldehyde is 41-43 °C(lit.). |
| Q: What are the downstream products of 2-Hydroxy-4-methoxybenzaldehyde? |
| A: Related downstream products(CAS) of 2-Hydroxy-4-methoxybenzaldehyde: 108530-10-5;107811-48-3;3722-56-3;50551-61-6;39835-11-5;50551-63-8;4107-65-7;484-12-8;42327-52-6;208842-22-2. |
| Q: What is the molecular formula of 2-Hydroxy-4-methoxybenzaldehyde? |
| A: Molecular formula of 2-Hydroxy-4-methoxybenzaldehyde is C8H8O3. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |
| naturewill |
| Henan Tianfu Chemical Co., Ltd. |