(Tyr4)-Bombesin

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Names

[ Name ]:
(Tyr4)-Bombesin

[Synonym ]:
PYROGLU-GLN-ARG-TYR-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET NH2
L-Methioninamide, 5-oxo-L-prolyl-L-glutaminyl-L-arginyl-L-tyrosylglycyl-L-asparaginyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-
GLP-GLN-ARG-TYR-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
5-Oxo-L-prolyl-L-glutaminyl-L-arginyl-L-tyrosylglycyl-L-asparaginyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-L-methioninamide
PGLU-GLN-ARG-TYR-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
5-Oxo-L-Pro-L-Gln-L-Arg-Tyr-Gly-L-Asn-L-Gln-L-Trp-L-Ala-L-Val-Gly-L-His-L-Leu-L-Met-NH2
PYR-QRYGNQWAVGHLM-NH2
bombesin-4-L-tyrosine

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₇₄H₁₀₈N₂₄O₁₉S

[ Molecular Weight ]:
1669.864

[ Exact Mass ]:
1668.794312

[ PSA ]:
731.66000

[ LogP ]:
-4.93

[ Index of Refraction ]:
1.693

[ Storage condition ]:
-20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Articles

Bombesin receptors in distinct tissue compartments of human pancreatic diseases.

Lab. Invest. 80 , 1807-1817, (2000)

Overexpression of receptors for regulatory peptides in various human diseases is reportedly of clinical interest. Among these peptides, bombesin and gastrin-releasing peptide (GRP) have been shown to ...

Modulation of bombesin-induced phosphatidylinositol hydrolysis in a small-cell lung-cancer cell line.

Biochem. J. 255 , 403-410, (1988)

Bombesin is an amphibian tetradecapeptide whose mammalian homologue, gastrin-releasing peptide (GRP), is produced by many small-cell lung-cancer (SCLC) cells, and which can function in an autocrine gr...

Investigation of molecular structure of bombesin and its modified analogues nonadsorbed and adsorbed on electrochemically roughened silver surface.

Biopolymers 89 , 506-521, (2008)

This work describes the molecular structure of bombesin (BN) and its analogs on the basis of the absorption infrared and Raman results described below. In these analogues is replaced one ([D-Phe12]BN,...

[Pro1,Tyr4]bombesin (1-14) synthetic GRP receptor ligand.
(Tyr4,D-Phe12)-Bombesin
(Lys3)-Bombesin
(D-Phe12)-Bombesin
(D-Phe12,Leu14)-Bombesin
(Leu13-psi(CH2NH)Leu14)-Bombesin
2-fluoro-N-(2-methylcyclohexyl)pyridine-4-carboxamide
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
4-(Carbamoylmethoxy)benzene-1-sulfonyl fluoride
tert-Butyl-DL-alanine