9-Hydroxycamptothecin

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Names

[ CAS No. ]:
67656-30-8

[ Name ]:
9-Hydroxycamptothecin

[Synonym ]:
10-Hydroxycamptothecin
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (4S)-
hydroxycamtothecine
Camptothecin, 10-hydroxy
9-hydroxy-20(S)-camptothecin
10-hydroxy-Camptothecin
9-hydroxy-2,2-dimethyl-3,4-dihydro-2H-benzo[g] chromene-5,10-dione
(4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
3,4-dihydro-9-hydroxy-2,2-dimethyl-2H-benzo[g]chromene-5,10

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
820.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H16N2O5

[ Molecular Weight ]:
364.351

[ Flash Point ]:
450.1±34.3 °C

[ Exact Mass ]:
364.105927

[ PSA ]:
101.65000

[ LogP ]:
1.32

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.777

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Camptothecin N-oxide
  • 9-Aminocamptothecin
  • rubitecan
  • 2,6-Dinitrobenzaldehyde
  • (S)-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
  • 2-amino-6-nitrobenzaldehyde ethylene acetal
  • Campathecin

DownStream

  • 9-Methoxycamptothecine

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 9-Hydroxycamptothecin
  • 12-Ethyl-9-hydroxycamptothecin
  • 9-chloro-5-methoxy-3-nitroacridine
  • 9-(2-prop-1-enoxyethyl)carbazole
  • 9-Amino-10,10-dimethyl-9,10-dihydro-10-sila-2-azaanthracene
  • 9-phenylnon-8-enal
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-(2-Piperazin-1-ylethyl)pyrrolidin-2-one
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • N'-[1-(3,4-dichlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-3-hydroxybenzohydrazide
  • tert-Butyl-DL-alanine