9-Hydroxycamptothecin
Modify Date: 2025-08-21 12:34:36
9-Hydroxycamptothecin structure
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Common Name | 9-Hydroxycamptothecin | ||
|---|---|---|---|---|
| CAS Number | 67656-30-8 | Molecular Weight | 364.351 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 820.7±65.0 °C at 760 mmHg | |
| Molecular Formula | C20H16N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 450.1±34.3 °C | |
Use of 9-Hydroxycamptothecin9-Hydroxycamptothecin (9-Hydroxycamptothecine) is a Camptothecin derivative with anticancer activities extracted from patent WO1999001456A1, compound 23c[1]. |
| Name | 3,4-dihydro-9-hydroxy-2,2-dimethyl-2H-benzo[g]chromene-5,10-dione |
|---|---|
| Synonym | More Synonyms |
| Description | 9-Hydroxycamptothecin (9-Hydroxycamptothecine) is a Camptothecin derivative with anticancer activities extracted from patent WO1999001456A1, compound 23c[1]. |
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| Related Catalog | |
| References |
[1]. Dennis P. Curran, et al. Synthesis of and intermediates for camptothecins. WO1999001456A1. |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 820.7±65.0 °C at 760 mmHg |
| Molecular Formula | C20H16N2O5 |
| Molecular Weight | 364.351 |
| Flash Point | 450.1±34.3 °C |
| Exact Mass | 364.105927 |
| PSA | 101.65000 |
| LogP | 1.32 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Index of Refraction | 1.777 |
| InChIKey | LCZZWLIDINBPRC-FQEVSTJZSA-N |
| SMILES | CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(O)cccc3nc2-1 |
| Hazard Codes | Xn |
|---|---|
| HS Code | 2934999090 |
CAS#:86639-48-7
CAS#:91421-43-1
CAS#:91421-42-0
CAS#:606-31-5![(S)-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione Structure](https://image.chemsrc.com/caspic/225/110351-94-5.png)
CAS#:110351-94-5
CAS#:151585-78-3
CAS#:7689-03-4
CAS#:39026-92-1| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1303_AS
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Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
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Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1303_FP
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Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
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Name: Confirmation Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1)
Source: NCGC
Target: Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1)
External Id: TDP1640
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Name: Inhibition of calf thymus DNA topoisomerase 1-mediated relaxation of supercoiled pBR3...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2427939
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Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
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Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100
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Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
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Name: Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H...
Source: Southern Research Institute
Target: CFTR
External Id: CF Folding
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| 10-Hydroxycamptothecin |
| hydroxycamtothecine |
| Camptothecin, 10-hydroxy |
| 9-hydroxy-20(S)-camptothecin |
| 10-hydroxy-Camptothecin |
| 9-hydroxy-2,2-dimethyl-3,4-dihydro-2H-benzo[g] chromene-5,10-dione |
| (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
| 3,4-dihydro-9-hydroxy-2,2-dimethyl-2H-benzo[g]chromene-5,10 |