(4S)-1-(tert-Butoxycarbonyl)-4-fluor-D-prolin

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Names

[ Name ]:
(4S)-1-(tert-Butoxycarbonyl)-4-fluor-D-prolin

[Synonym ]:
(4S)-1-(tert-butoxycarbonyl)-4-fluoro-D-proline
(4S)-4-Fluoro-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline
(4S)-1-(tert-Butoxycarbonyl)-4-fluor-D-prolin
1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) ester, (2R,4S)-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
346.0±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₆FNO₄

[ Molecular Weight ]:
233.237

[ Flash Point ]:
163.0±27.9 °C

[ Exact Mass ]:
233.106339

[ PSA ]:
66.84000

[ LogP ]:
0.48

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.488

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(2R,4S)-4-fluoro-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
D-Proline, 4-hydroxy-, methyl ester hydrochloride
N-Boc-cis-4-hydroxy-D-proline methyl ester
cis-4-Hydroxyproline

DownStream

Related Compounds

(4S)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline benzyl ester
(4S)-1-(tert-Butoxycarbonyl)-4-methyl-L-proline
(4S)-1-(tert-butoxycarbonyl)-4-((methylsulfonyl)oxy)-L-proline benzyl ester
tert-Butyl (2S,4S)-2-carbamoyl-4-hydroxypyrrolidine-1-carboxylate
(4S)-1-(tert-Butoxycarbonyl)-4-(4-chloro-3,5-dimethylphenoxy)-L-proline
(4S)-1-tert-butoxycarbonyl-4-(4-chlorophenyl)-2-pyrrolidone
4-[[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl]phenol
3-[[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl]phenol
2-Benzyloxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
3-[[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl]phenol
4,4,5,5-Tetramethyl-2-[1-methyl-1-[3-(o-tolyl)-1-bicyclo[1.1.1]pentanyl]ethyl]-1,3,2-dioxaborolane
4,4,5,5-tetramethyl-2-[(2R)-2-[3-(o-tolyl)-1-bicyclo[1.1.1]pentanyl]propyl]-1,3,2-dioxaborolane
2-(2-Butyl-3-phenyl-1-bicyclo[1.1.1]pentanyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1-(3-Chloroprop-1-en-2-yl)-3-cyclopropylbenzene
cis-1-benzyl-2,6-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine
2-[2-Fluoro-5-(phenoxymethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

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