GW4869

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Names

[ CAS No. ]:
6823-69-4

[ Name ]:
GW4869

[Synonym ]:
GW 4869 (hydrochloride hydrate)

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₃₀Cl₂N₆O₂

[ Molecular Weight ]:
577.50

[ PSA ]:
127.21000

[ LogP ]:
4.57730

[ Storage condition ]:
-20℃

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Glutaminase-containing microvesicles from HIV-1-infected macrophages and immune-activated microglia induce neurotoxicity.

Molecular Neurodegeneration 10 , 61, (2015)

HIV-1-infected and/or immune-activated microglia and macrophages are pivotal in the pathogenesis of HIV-1-associated neurocognitive disorders (HAND). Glutaminase, a metabolic enzyme that facilitates g...

Regulation of SREBPs by Sphingomyelin in Adipocytes via a Caveolin and Ras-ERK-MAPK-CREB Signaling Pathway.

PLoS ONE 10 , e0133181, (2015)

Sterol response element binding protein (SREBP) is a key transcription factor in insulin and glucose metabolism. We previously demonstrated that elevated levels of membrane sphingomyelin (SM) were rel...

Secretion of small/microRNAs including miR-638 into extracellular spaces by sphingomyelin phosphodiesterase 3.

Oncol. Rep. 33(1) , 67-73, (2014)

A recent study demonstrated that intracellular small/microRNAs are released from cells, and some of these extracellular RNAs are embedded in vesicles, such as ceramide-rich exosomes, on lipid-bilayer ...

3-[(2,5-Dimethylfuran-3-yl)methyl]pyrrolidine
Methyl 4-(2-amino-1-fluoroethyl)-2-methylbenzoate
methyl 5-[1-(hydroxymethyl)cyclopropyl]-1-methyl-1H-pyrazole-4-carboxylate
rac-(1R,2R)-2-[4-(methoxycarbonyl)-1-methyl-1H-pyrazol-5-yl]cyclopropane-1-carboxylic acid
methyl 5-[(1S)-1-aminoethyl]-1-methyl-1H-pyrazole-4-carboxylate
methyl 5-(4-aminobutan-2-yl)-1-methyl-1H-pyrazole-4-carboxylate
3-[4-(methoxycarbonyl)-1-methyl-1H-pyrazol-5-yl]butanoic acid
methyl 1-methyl-5-(piperidin-4-yl)-1H-pyrazole-4-carboxylate
3,5-dimethyl-4-(2-methyloxiran-2-yl)-1-(propan-2-yl)-1H-pyrazole
3-[3,5-dimethyl-1-(propan-2-yl)-1H-pyrazol-4-yl]prop-2-enal

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