GW4869

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Names

[ CAS No. ]:
6823-69-4

[ Name ]:
GW4869

[Synonym ]:
GW 4869 (hydrochloride hydrate)

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₃₀Cl₂N₆O₂

[ Molecular Weight ]:
577.50

[ PSA ]:
127.21000

[ LogP ]:
4.57730

[ Storage condition ]:
-20℃

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Glutaminase-containing microvesicles from HIV-1-infected macrophages and immune-activated microglia induce neurotoxicity.

Molecular Neurodegeneration 10 , 61, (2015)

HIV-1-infected and/or immune-activated microglia and macrophages are pivotal in the pathogenesis of HIV-1-associated neurocognitive disorders (HAND). Glutaminase, a metabolic enzyme that facilitates g...

Regulation of SREBPs by Sphingomyelin in Adipocytes via a Caveolin and Ras-ERK-MAPK-CREB Signaling Pathway.

PLoS ONE 10 , e0133181, (2015)

Sterol response element binding protein (SREBP) is a key transcription factor in insulin and glucose metabolism. We previously demonstrated that elevated levels of membrane sphingomyelin (SM) were rel...

Secretion of small/microRNAs including miR-638 into extracellular spaces by sphingomyelin phosphodiesterase 3.

Oncol. Rep. 33(1) , 67-73, (2014)

A recent study demonstrated that intracellular small/microRNAs are released from cells, and some of these extracellular RNAs are embedded in vesicles, such as ceramide-rich exosomes, on lipid-bilayer ...

(3S)-3-[(3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]heptanoic acid
(2R)-4-[4-chloro-2-(trifluoromethyl)phenyl]butan-2-amine
5-(3,4-Difluorophenyl)-1,2,3,6-tetrahydropyridin-3-ol
4-[2-Methoxy-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine
5-Bromo-2-[(pent-1-yn-3-yl)amino]pyrimidine-4-carboxylic acid
4-Oxo-1,4-dihydroquinoline-8-sulfonyl fluoride
4-Fluorooxolane-3-sulfonyl fluoride
(1R)-1-{imidazo[1,2-a]pyridin-2-yl}-2,2-dimethylpropan-1-amine
1-[2-(4-Chloro-3-methoxyphenyl)ethyl]cyclopropan-1-ol
2-(2-Amino-1-fluoroethyl)-4-nitrophenol

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