Ginsenoside Rb3

Suppliers

Names

[ Name ]:
Ginsenoside Rb3

[Synonym ]:
20(S)-ginsenoside Rg3
20-((6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy)-12β-hydroxydammar-24-en-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
(3β,12β)-20-{[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 6-O-β-D-xylopyranosyl-α-D-glucopyranoside
Ginsenoside Rg3 (R-)
ginsenoside-RB2
20(R)Ginsenoside Rg3
(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
GinsenosideRb3
(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxyméthyl)-2-({(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentaméthyl-17-[(2S)-6-méthyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S)-3,4,5-trihydroxytétrahydro-2H-pyran-2-yl]oxy}méthyl)tétrahydro-2H-pyran-2-yl]oxy}-5-heptèn-2-yl]hexadécahydro-1H-cyclopenta[a]phénanthrén-3-yl}oxy)tétrahydro-2H-pyran-3-yl]oxy}-6-(hydroxyméthyl)tétrahydro-2H-pyran-3,4,5-triol
3-epicabraleahydroxylactone
(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-({(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-5-hepten-2-yl]hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl}oxy)tetrahydro-2H-pyran-3-yl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(3β,12β)-20-{[6-O-(α-L-Arabinopyranosyl)-β-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranoside
3|A-Acetoxy-22,23-dinorchol-5-en-24-al
(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(1R)-1-hydroxy-1,5-dimethyl-hex-4-enyl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-methylol-tetrahydropyran-3-yl]oxy-6-methylol-tetrahydropyran-3,4,5-triol
Ginsenoside Rb3
α-D-Glucopyranoside, (3β,12β)-20-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 6-O-β-D-xylopyranosyl-
(3|A,20S)-20-Formyl-3-hydroxy-5-pregnene 3-O-AcetateDiscontinued
(3β,12β)-20-{[6-O-(α-L-Arabinopyranosyl)-β-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
Ginsenoside Rg3 Rh2
β-D-Glucopyranoside, (3β,12β)-20-[(6-O-α-L-arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
(20S)-3|A-Acetoxypregn-5-ene-20-carboxaldehyde
(3|A,20S)-3-(Acetyloxy)pregn-5-ene-20-carboxaldehyde
R-form-Ginsenoside Rg3
GINSENOSIDE RG3(R-FORM)(P)
3|A-Acetoxybisnor-5-cholen-22-al

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1117.1±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅₃H₉₀O₂₂

[ Molecular Weight ]:
1079.269

[ Flash Point ]:
629.4±34.3 °C

[ Exact Mass ]:
1078.592407

[ PSA ]:
357.06000

[ LogP ]:
4.73

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.622

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ5857000

CHEMICAL NAME :: alpha-D-Glucopyranoside, (3-beta,12-beta)-3-((2-O-beta-D-glucopyranosyl-beta-D -glucopyranosyl)oxy)- 12-hydroxydammar-24-en-20-yl 6-O-beta-D-xylopyranosyl-

CAS REGISTRY NUMBER :: 68406-26-8

LAST UPDATED :: 199312

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C53-H90-O22

MOLECULAR WEIGHT :: 1079.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 637 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2430234

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
LZ5857000

[ HS Code ]:
29389090

Articles

[A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].

Yao Xue Xue Bao 43(12) , 1211-6, (2008)

Current quality control patterns are limited to industrial application, for most of the natural chemical reference substances are expensive and unavailable. Herein, a method, quantitative analysis of ...

Inhibition of NMDA receptors underlies the neuroprotective effect of ginsenoside Rb3.

Am. J. Chin. Med. 37(4) , 759-70, (2009)

In order to investigate the mechanisms underlying the neuroprotective effect of ginsenoside Rb3, rat hippocampal neurons were primarily cultured, and exposed to 1 mM N-methyl-D-aspartate (NMDA), cell ...

Ginsenoside Rb3 ameliorates myocardial ischemia-reperfusion injury in rats.

Pharm. Biol. 49(9) , 900-6, (2011)

Panax ginseng C. A. Mey (Araliaceae) has been widely used in clinic for treatment of cardiovascular diseases in China. Ginsenoside Rb3 is the main chemical component of Panax ginseng.The aim of this s...