Cilostamide

Suppliers

Names

[ CAS No. ]:
68550-75-4

[ Name ]:
Cilostamide

[Synonym ]:
Butanamide, N-cyclohexyl-4-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methyl-
N-Cyclohexyl-N-methyl-4-[(2-oxo-1,2-dihydro-6-quinolinyl)oxy]butanamide
MFCD00673958
N-Cyclohexyl-N-methyl-4-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]butanamide
N-cyclohexyl-N-methyl-4-[(2-oxo-1H-quinolin-6-yl)oxy]butanamide
N-cyclohexyl-4-[(2-hydroxyquinolin-6-yl)oxy]-N-methylbutanamide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
594.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H26N2O3

[ Molecular Weight ]:
342.432

[ Flash Point ]:
313.2±30.1 °C

[ Exact Mass ]:
342.194336

[ PSA ]:
62.40000

[ LogP ]:
2.70

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.586

[ Storage condition ]:
-20℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
UN 3249

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Synthetic Route

Precursor & DownStream

Precursor

  • N-Methylcyclohexanamine
  • 4-[(2-oxo-1H-quinolin-6-yl)oxy]butanoic acid
  • 5-Hydroxy-2-nitrobenzaldehyde
  • N-cyclohexyl-N-methyl-4-[3-(2-carboxyvinyl)-4-nitrophenoxy]butyramide
  • 4-(3-FORMYL-4-NITRO-PHENOXY)-BUTYRIC ACID
  • 6-Hydroxyquinolin-2(1H)-one

DownStream

Articles

Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle.

J. Pharmacol. Exp. Ther. 350(3) , 681-90, (2014)

We previously found a negative inotropic (NIR) and positive lusitropic response (LR) to C-type natriuretic peptide (CNP) in the failing heart ventricle. In this study, we investigated and compared the...

Adenylyl cyclases 5 and 6 underlie PIP3-dependent regulation.

FASEB J. 29 , 3458-71, (2015)

Many different neurotransmitters and hormones control intracellular signaling by regulating the production of the second messenger cAMP. The function of the broadly expressed adenylyl cyclases (ACs) 5...

Lymphatic vascular integrity is disrupted in type 2 diabetes due to impaired nitric oxide signalling.

Cardiovasc. Res. 107 , 89-97, (2015)

Lymphatic vessel dysfunction is an emerging component of metabolic diseases and can lead to tissue lipid accumulation, dyslipidaemia, and oedema. While lymph leakage has been implicated in obesity and...


More Articles


Related Compounds

  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl thieno[3,2-b]furan-5-carboxylate
  • 3-amino-2,3-dihydro-1H-indene-4,5-dicarboxylic acid hydrochloride
  • 3-amino-2,3-dihydro-1H-indene-4,5-dicarboxylic acid
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-methyl-5-(methylsulfamoyl)benzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-(2-methanesulfonamidoethyl)thiophene-2-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-methoxy-4-(prop-2-en-1-yloxy)benzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-acetyl-2,3-dihydro-1H-indole-5-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-methyl-6-(thiophen-2-yl)pyridine-3-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-[2,4,5-trioxo-3-(prop-2-en-1-yl)imidazolidin-1-yl]acetate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-oxo-1-phenyl-2,5-dihydro-1H-pyrazole-3-carboxylate
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