N6-acetyl-L-lysine

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Names

[ CAS No. ]:
692-04-6

[ Name ]:
N6-acetyl-L-lysine

[Synonym ]:
Ne-Acetyl-L-lysine
Ne-Acetyllysine
MFCD00002639
N-ε-ACETYL-L-LYSINE
L-Lysine, N-acetyl-
N(6)-acetyl-L-lysine
(S)-6-Acetamido-2-aminohexanoic acid
L-Lysine, N-(1-hydroxyethylidene)-, (Z)-
N-Acetyl-L-lysine
(Z)-N-(1-Hydroxyethylidene)-L-lysine
EINECS 211-725-9
H-Lys(Ac)-OH
N-epsilon-Acetyl-L-lysine
Nε-Acetyl-L-lysine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
442.0±40.0 °C at 760 mmHg

[ Melting Point ]:
250 °C (dec.)(lit.)

[ Molecular Formula ]:
C8H16N2O3

[ Molecular Weight ]:
188.224

[ Flash Point ]:
221.1±27.3 °C

[ Exact Mass ]:
188.116089

[ PSA ]:
92.42000

[ LogP ]:
-1.42

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.490

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29241900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • L-Lysine
  • Ethanoic anhydride
  • Boc-Lys(Ac)-OH
  • Methylglyoxal
  • L-(+)-Lysine monohydrochloride
  • N-Boc-L-lysine
  • Phenylacetic acid
  • P-NITROPHENYLACETATE
  • lysine acetylsalicylate
  • Aspirin

DownStream

  • L(-)-Pipecolinic acid
  • Boc-Lys(Ac)-OH
  • AC-DL-LYS (AC)-OH

Articles

Hypernuclear acetylation in atherosclerotic lesions and activated vascular smooth muscle cells.

Biochem. Biophys. Res. Commun. 266(2) , 417-24, (1999)

Recent studies have implicated acetylation of several nuclear proteins such as histones and p53 on their epsilon-portion of lysine residues in eukaryotic transcription. Here we raised a specific polyc...

Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies.

Proteomics 5(18) , 4653-64, (2005)

Post-translational lysine-acetylation and -methylation are two major PTMs of lysine residues in proteins. Recently, we established pan-reactive anti-acetyllysine mouse mAbs, which can bind to Nepsilon...

Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis.

Biosci. Biotechnol. Biochem. 69 , 1914-1922, (2005)

A novel aminoacylase was purified to homogeneity from culture broth of Streptomyces mobaraensis, as evidenced by SDS-polyacrylamide gel electrophoresis (PAGE). The enzyme was a monomer with an approxi...


More Articles

Related Compounds

  • N6-Acetyl-L-lysine hydrochloride (1:1)
  • N-Acetyl-L-Lysine Amide Hydrochloride
  • Boc-Lys(Ac)-OH
  • N(6)-acetyl-N(6)-hydroxylysine
  • FMOC-N'-ACETYL-L-LYSINE
  • n-alpha-acetyl-l-lysine-n-methylamide monohydrate
  • 4-tert-butyl-2-oxo-N-[(pyridin-2-yl)methyl]pyrrolidine-3-carboxamide
  • 4-tert-butyl-N-[4-fluoro-3-(trifluoromethyl)phenyl]-2-oxopyrrolidine-3-carboxamide
  • 4-tert-butyl-N-(5-hydroxy-1-phenyl-1H-pyrazol-3-yl)-2-oxopyrrolidine-3-carboxamide
  • 4-Tert-butyl-3-[4-(2,3-dichlorophenyl)piperazine-1-carbonyl]pyrrolidin-2-one
  • 4-tert-butyl-2-oxo-N-(2-oxothiolan-3-yl)pyrrolidine-3-carboxamide
  • 4-Tert-butyl-3-(4-cyclohexylpiperazine-1-carbonyl)pyrrolidin-2-one
  • 4-Tert-butyl-3-(4-methanesulfonylpiperazine-1-carbonyl)pyrrolidin-2-one
  • 4-Tert-butyl-3-{4-[(pyridin-2-yl)methyl]piperazine-1-carbonyl}pyrrolidin-2-one
  • 2-(4-tert-butyl-2-oxopyrrolidine-3-amido)-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
  • Methyl 2-(4-tert-butyl-2-oxopyrrolidine-3-amido)thiophene-3-carboxylate
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