N6-acetyl-L-lysine

Modify Date: 2026-07-03 16:47:09

N6-acetyl-L-lysine Structure
N6-acetyl-L-lysine structure
Common Name N6-acetyl-L-lysine
CAS Number 692-04-6 Molecular Weight 188.224
Density 1.1±0.1 g/cm3 Boiling Point 442.0±40.0 °C at 760 mmHg
Molecular Formula C8H16N2O3 Melting Point 250 °C (dec.)(lit.)
MSDS USA Flash Point 221.1±27.3 °C

 Use of N6-acetyl-L-lysine


Nepsilon-Acetyl-L-lysine is a derivative of the amino acid lysine.

 Names

Name N6-acetyl-L-lysine
Synonym More Synonyms

 N6-acetyl-L-lysine Biological Activity

Description Nepsilon-Acetyl-L-lysine is a derivative of the amino acid lysine.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Schmidt H, et al. Characterization of a novel enzyme, N6-acetyl-L-lysine: 2-oxoglutarate aminotransferase, which catalyses the second step of lysine catabolism in Candida maltosa. Antonie Van Leeuwenhoek. 1992 Nov;62(4):285-90.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 442.0±40.0 °C at 760 mmHg
Melting Point 250 °C (dec.)(lit.)
Molecular Formula C8H16N2O3
Molecular Weight 188.224
Flash Point 221.1±27.3 °C
Exact Mass 188.116089
PSA 92.42000
LogP -1.42
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.490
InChIKey DTERQYGMUDWYAZ-ZETCQYMHSA-N
SMILES CC(=O)NCCCCC(N)C(=O)O
Storage condition −20°C

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 29241900

 Synthetic Route

 Articles32

More Articles
Hypernuclear acetylation in atherosclerotic lesions and activated vascular smooth muscle cells.

Biochem. Biophys. Res. Commun. 266(2) , 417-24, (1999)

Recent studies have implicated acetylation of several nuclear proteins such as histones and p53 on their epsilon-portion of lysine residues in eukaryotic transcription. Here we raised a specific polyc...

Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies.

Proteomics 5(18) , 4653-64, (2005)

Post-translational lysine-acetylation and -methylation are two major PTMs of lysine residues in proteins. Recently, we established pan-reactive anti-acetyllysine mouse mAbs, which can bind to Nepsilon...

Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis.

Biosci. Biotechnol. Biochem. 69 , 1914-1922, (2005)

A novel aminoacylase was purified to homogeneity from culture broth of Streptomyces mobaraensis, as evidenced by SDS-polyacrylamide gel electrophoresis (PAGE). The enzyme was a monomer with an approxi...

 N6-acetyl-L-lysineBioassay

View more

Name: Inhibition of wild-type Bacillus subtilis 168 1A1 lysine riboswitch 179 lysc assessed...
Source: ChEMBL
Target: Nucleic Acid
External Id: CHEMBL1250158
Name: Binding affinity to Bacillus subtilis 168 1A1 lysine riboswitch 179 lysc by in-line p...
Source: ChEMBL
Target: Nucleic Acid
External Id: CHEMBL1250155
Name: Antibacterial activity against Bacillus subtilis 168 1A1 after 24 hrs by CLSI method
Source: ChEMBL
Target: Bacillus subtilis
External Id: CHEMBL1250169
Total 3, Current Page 1 of 1
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 Synonyms

Ne-Acetyl-L-lysine
Ne-Acetyllysine
MFCD00002639
N-ε-ACETYL-L-LYSINE
N(6)-acetyl-L-lysine
(S)-6-Acetamido-2-aminohexanoic acid
N-Acetyl-L-lysine
(Z)-N-(1-Hydroxyethylidene)-L-lysine
EINECS 211-725-9
H-Lys(Ac)-OH
N-epsilon-Acetyl-L-lysine
Nε-Acetyl-L-lysine
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