2'-Fluoro-5-methylarabinosyluracil

Suppliers

Names

[ CAS No. ]:
69256-17-3

[ Name ]:
2'-Fluoro-5-methylarabinosyluracil

[Synonym ]:
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluracil
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C10H13FN2O5

[ Molecular Weight ]:
260.22

[ Exact Mass ]:
260.080841

[ PSA ]:
104.55000

[ LogP ]:
-0.72

[ Index of Refraction ]:
1.593

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ9512600
CHEMICAL NAME :
Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl -
CAS REGISTRY NUMBER :
69256-17-3
LAST UPDATED :
198303
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H13-F-N2-O5
MOLECULAR WEIGHT :
260.25
WISWESSER LINE NOTATION :
T6NVMVJ E1 A- BT5OTJ CF DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - mouse Leukocyte
DOSE/DURATION :
17 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,3957,1982

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-methyl-β-D-arabino-uridine
  • 1-(3-O-Acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)thymine
  • 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose
  • 2-Deoxy-2-fluoro-alpha-D-arabinofuranosyl bromide 3,5-dibenzoate
  • 5-METHYLCYTOSINE
  • 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide
  • 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranose
  • 1-(3-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methylcytosine
  • Thymine
  • bis(o-trimethylsilyl)thymine

DownStream

  • 1-[(2R,3S,4R,5S)-3-fluoro-4-hydroxy-5-(sulfanylmethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
  • 5'-O-Dimethoxytrityl-deoxythymidine
  • Trityl-lyxofuranosyl-T
  • Anhydro nucleoside
  • [(2R,3R,4R,5R)-3,4-difluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl benzoate

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2'-Fluoro-5-ethylarabinosyluracil
  • 2'-fluoro-5-bromo-1-beta-D-arabinofuranosylcytosine
  • 2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine
  • 2'-FLUORO-5-METHOXY-5'-METHYL-[1,1'-BIPHENYL]-3-CARBOXYLIC ACID
  • 2'-fluoro-5-nitrobiphenyl-2-ol
  • 2'-fluoro-5-chloro-1-beta-D-arabinofuranosylcytosine
  • 2-Chloro-N-(2-methyl-1-oxo-3,4-dihydroisoquinolin-6-yl)propanamide
  • 4-(2-Chloropropanoyl)-1-(cyclopentylmethyl)piperazin-2-one
  • (E)-4-(Dimethylamino)-N-(1-pyrimidin-4-ylazetidin-3-yl)but-2-enamide
  • 2-Chloro-N-[4-(difluoromethoxy)-5-fluoro-2-(1,2,4-triazol-1-yl)phenyl]propanamide
  • N-(1-Acetylpiperidin-4-yl)-2-chloro-N-(1,3-thiazol-5-ylmethyl)propanamide
  • 2-chloro-N-[8-(2-methoxyethyl)-8-azabicyclo[3.2.1]octan-3-yl]-N-methylpropanamide
  • 3-{1-[4-(2-Chloropropanoyl)piperazin-1-yl]ethyl}benzonitrile
  • 2-Chloro-1-{3-[(2,4-difluorophenyl)methyl]-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl}propan-1-one
  • 2-Chloro-N-[1-(5-fluoro-1-methylindol-3-yl)propan-2-yl]propanamide
  • 2-Chloro-1-[2-[(3,4-difluorophenoxy)methyl]morpholin-4-yl]propan-1-one
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.