2'-Fluoro-5-methylarabinosyluracil

Modify Date: 2024-01-04 14:36:14

2'-Fluoro-5-methylarabinosyluracil Structure
2'-Fluoro-5-methylarabinosyluracil structure
Common Name 2'-Fluoro-5-methylarabinosyluracil
CAS Number 69256-17-3 Molecular Weight 260.22
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H13FN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-Fluoro-5-methylarabinosyluracil


FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

 Names

Name 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil
Synonym More Synonyms

 2'-Fluoro-5-methylarabinosyluracil Biological Activity

Description FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
Related Catalog
References

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C10H13FN2O5
Molecular Weight 260.22
Exact Mass 260.080841
PSA 104.55000
LogP -0.72
Index of Refraction 1.593

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ9512600
CHEMICAL NAME :
Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl -
CAS REGISTRY NUMBER :
69256-17-3
LAST UPDATED :
198303
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H13-F-N2-O5
MOLECULAR WEIGHT :
260.25
WISWESSER LINE NOTATION :
T6NVMVJ E1 A- BT5OTJ CF DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - mouse Leukocyte
DOSE/DURATION :
17 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,3957,1982

 Safety Information

HS Code 2934999090

 Synthetic Route

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluracil
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
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